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Chest:饮酒对急性呼吸窘迫综合征风险的影响!

2017-12-31 xing.T MedSci原创

由此可见,长期较高的酒精消耗量显著增加ARDS的风险。这一发现表明住院的病人应该接受长期饮酒的筛查。

近日,呼吸领域权威杂志chest上发表了一篇荟萃分析文章,研究人员旨在评估饮酒量与急性呼吸窘迫综合征(ARDS)风险之间的关系。

研究人员检索了MEDLINE、EMBASE和Web of Science等数据库确定了评估既往饮酒与成人ARDS发生之间相关性的观察性研究,并且这些研究发表于1985年至2015年之间,没有语言限制。研究人员还筛选了参考文献列表。人口基线数据由两名评审者独立提取,随机效应荟萃分析被用于估计合并效应大小和95%可信区间。亚组分析用于探索异质性。

十七项观察性研究(177674名参与者)符合纳入标准。十三研究的荟萃分析表明任何高酒精消耗量的指标与ARDS风险显著增加相关(比值比为1.89,95%可信区间为1.45-2.48,I2=48%,13项研究);未观察到发表偏倚的证据(P=0.150)。敏感性分析表明这种相关性主要归因于酗酒史(比值比为1.90,95%可信区间为1.40-2.60,10项研究)。此外,亚组分析发现异质性可被易感因素(创伤、败血症/感染性休克、肺炎,P=0.003)所解释。

由此可见,长期较高的酒精消耗量显著增加ARDS的风险。这一发现表明住院的病人应该接受长期饮酒的筛查

原始出处:

Evangelia Simou,et al. The effect of alcohol consumption on the risk of ARDS. A systematic review and meta-analysis.chest.2017. http://dx.doi.org/10.1016/j.chest.2017.11.041

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    2018-10-27 Smile2680
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    2018-01-12 1dd8c52fm63(暂无匿称)

    了解了解.学习学习

    0

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