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CLIN CHEM:利用单指纹技术无创检测可卡因和海洛因使用情况

2018-06-21 MedSci MedSci原创

最近发表的研究探索了利用指纹来确认药物使用的可能性,但是还没有排除指尖环境的污染。在本研究中,研究人员探索了从单个指纹建立药物测试环境临界值的可能性。 在50名非药物使用者洗手前后收集指纹样本(n = 100)以建立单独的环境临界值和对可卡因,苯甲酰芽子碱,海洛因和6-单乙酰吗啡的测试方案。与毒品使用者握手后,通过测试无药物志愿者的指纹来测定临界值。此外,本研究还收集并分析了经证实服用过可卡

最近发表的研究探索了利用指纹来确认药物使用的可能性,但是还没有排除指尖环境的污染。在本研究中,研究人员探索了从单个指纹建立药物测试环境临界值的可能性。 在50名非药物使用者洗手前后收集指纹样本(n = 100)以建立单独的环境临界值和对可卡因,苯甲酰芽子碱,海洛因和6-单乙酰吗啡的测试方案。与毒品使用者握手后,通过测试无药物志愿者的指纹来测定临界值。此外,本研究还收集并分析了经证实服用过可卡因(n = 32)和海洛因(n = 24)的患者的指纹。 研究发现,根据所提供的指纹是在洗手前还是洗手后收集的,需要应用不同的临界值。应用这些临界值使得无药物志愿者的假阳性率为0%。应用临界值后,患者洗手后的检出率(与患者证词相比)为使用可卡因87.5%,使用海洛因100%。 本研究表明,与被调查的初次吸毒人群相比,指纹图谱显示证实服用该物质的患者可卡因,海洛因及其各自代谢产物的水平增加,并且可以建立临界值(决定水平)。截止值足够强大,足以解释二次转移后观察到的分析物的小幅增加。 原始出处: Mahado Ismail, Derek Stevenson, Noninvasive Detection

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    2019-05-27 gous
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