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CMAJ:影响乳腺癌术后患者慢性疼痛的因素有哪些?

2016-07-12 MedSci MedSci原创

国际研究小组的研究人员已经确定了几个影响乳腺癌手术后持续性疼痛的风险因素,其中包括年龄较小、放疗、腋窝淋巴结清扫等,研究结果发表在CMAJ。 乳腺癌患者的10年生存率是83%左右。但是,25%-60%的妇女接受肿瘤切除术后发展为慢性疼痛。有哪些因素导致患者出息持续性的疼痛呢?为了深入探究导致患者手术后出现慢性疼痛的相关因素,来自加拿大、中国、巴西、西班牙和爱尔兰的研究人员对关于乳腺癌的30个研究数

国际研究小组的研究人员已经确定了几个影响乳腺癌手术后持续性疼痛的风险因素,其中包括年龄较小、放疗、腋窝淋巴结清扫等,研究结果发表在CMAJ。 


乳腺癌患者的10年生存率是83%左右。但是,25%-60%的妇女接受肿瘤切除术后发展为慢性疼痛。有哪些因素导致患者出息持续性的疼痛呢?

为了深入探究导致患者手术后出现慢性疼痛的相关因素,来自加拿大、中国、巴西、西班牙和爱尔兰的研究人员对关于乳腺癌的30个研究数据进行了系统回顾,参与人员共有19813名乳腺癌术后患者。 

麦克马斯特大学的Jason Busse博士指出,如果乳腺癌患者在切除肿瘤后进行淋巴结清扫时切断相关神经则易出现慢性疼痛。然而,研究人员并不能确定剥离神经预防慢性疼痛的效果。年轻、放疗、手术后急性疼痛也与慢性疼痛有关。最大的风险因素是腋窝淋巴结清扫,民众出现慢性疼痛的风险增加了21%,但是研究人员并不能为了减少患者出现慢性疼痛风险而保留相关神经,因为有可能导致患者出现并发症或再次手术的风险。

研究人员表示仍需进行更进一步的研究以探究相关风险,并采取措施减轻患者出现的慢性疼

原始出处:


拓展阅读:术后疼痛相关的拓展阅读:

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    2016-09-15 1e10c84am36(暂无匿称)

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  2. [GetPortalCommentsPageByObjectIdResponse(id=127109, encodeId=980112e109b0, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 15 07:25:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126770, encodeId=7ed9126e70e0, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 14 14:55:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119538, encodeId=dfff1195382a, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 17:01:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103079, encodeId=5c221030e9c6, content=什么破文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160417/IMG5713A450556263030.jpg, createdBy=b2e11713968, createdName=永恒光辉, createdTime=Wed Aug 24 15:12:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95556, encodeId=906d955563d, content=学习一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Aug 02 21:21:00 CST 2016, time=2016-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93160, encodeId=984793160b4, content=切断哪些神经呢,等于没说, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sat Jul 16 07:37:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260024, encodeId=053912600242e, content=<a href='/topic/show?id=fd52535e38b' target=_blank style='color:#2F92EE;'>#慢性疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53573, encryptionId=fd52535e38b, topicName=慢性疼痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=976a57, createdName=liubm555, createdTime=Thu Jul 14 09:25:00 CST 2016, time=2016-07-14, status=1, ipAttribution=)]
    2016-09-14 1e10c84am36(暂无匿称)

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    2016-09-10 1e10c84am36(暂无匿称)

    好文章,百姓也能从中学到好多医学知识

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=127109, encodeId=980112e109b0, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 15 07:25:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=126770, encodeId=7ed9126e70e0, content=文章不错,值得拜读, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 14 14:55:00 CST 2016, time=2016-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119538, encodeId=dfff1195382a, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 17:01:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=103079, encodeId=5c221030e9c6, content=什么破文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160417/IMG5713A450556263030.jpg, createdBy=b2e11713968, createdName=永恒光辉, createdTime=Wed Aug 24 15:12:00 CST 2016, time=2016-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=95556, encodeId=906d955563d, content=学习一下!, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Aug 02 21:21:00 CST 2016, time=2016-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=93160, encodeId=984793160b4, content=切断哪些神经呢,等于没说, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sat Jul 16 07:37:00 CST 2016, time=2016-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1260024, encodeId=053912600242e, content=<a href='/topic/show?id=fd52535e38b' target=_blank style='color:#2F92EE;'>#慢性疼痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53573, encryptionId=fd52535e38b, topicName=慢性疼痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=976a57, createdName=liubm555, createdTime=Thu Jul 14 09:25:00 CST 2016, time=2016-07-14, status=1, ipAttribution=)]
    2016-08-24 永恒光辉

    什么破文章

    0

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    2016-08-02 1dd8c52fm63(暂无匿称)

    学习一下!

    0

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    2016-07-16 oo902

    切断哪些神经呢,等于没说

    0

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