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Neurology:有癫痫,那就别趴着睡了,会死人的!

2015-07-09 sunshine 译 MedSci原创

有癫痫,那就别趴着睡了,会死人的!据最新发表于 Neurology的一项研究表明,患有癫痫而又习惯俯卧位睡觉的患者发生猝死的风险可能较其他体位睡觉的癫痫患者高。分析来自 PubMed,Web of Science以及Scopus databases的1106项研究,研究小组发现了其中的25项研究,共有包括253名癫痫患者在内的猝死病例,记录了患者死亡时的睡姿。研究人员发现,73.3%的病例死亡时的

据最新发表于 Neurology的一项研究表明,患有癫痫而又习惯俯卧位睡觉的患者发生猝死的风险可能较其他体位睡觉的癫痫患者高。

分析来自 PubMed,Web of Science以及Scopus databases的1106项研究,研究小组发现了其中的25项研究,共有包括253名癫痫患者在内的猝死病例,记录了患者死亡时的睡姿。

研究人员发现,73.3%的病例死亡时的睡姿为俯卧位,其余26.7%的病例死亡时为其他睡姿。其中有11例猝死病例通过了视频监控和脑电图检测(EEG),这11病例死亡时均为俯卧位睡眠姿势。

通过评估一项研究的88个病例,研究小组发现40岁以下患者死亡时采取俯卧位睡姿的数量为40岁以上猝死患者的4倍。

尽管研究人员并不确定为何年轻癫痫患者睡觉时发生猝死的风险较高,但是他们推测,可能是由于这些年轻患者单身的可能性大,所以睡眠时旁边没有其他人。 Dr. Tao指出,如果患者采取俯卧位睡眠,当癫痫发作时,应及时将其转换成其他体位。

研究人员对他们的研究成果如此评价:

“俯卧位睡眠与猝死之间存在显著的相关关系,表明俯卧位睡眠姿势是癫痫患者睡眠时发生猝死的一个主要危险因素,尤其是对于40岁及以下的患者。”

干预婴儿猝死综合症(SIDS)的措施可能对癫痫患者猝死同样有效

研究小组表示他们的研究发现癫痫患者猝死背后的机制可能与婴儿猝死综合症(SIDS)相似。

“SIDS患者,血清素含量较低,从而抑制了婴儿的自主复苏机制,且他们在柔软的地方处于俯卧位时睡眠时若呼吸道受阻,血清素含量低,则抑制了头部抬起或转向,”研究人员解释道。

Dr. Tao认为采用相似的策略可能有效的减小癫痫患者猝死的风险。“我们的发现强调预防癫痫患者猝死的重要策略——仰卧睡最佳,”Dr. Tao指出。“使用腕表和闹钟来检测患者睡眠时癫痫发作,这可能有助于预防猝死的发生。”

本研究的通讯作者Dr. Barbara Dworetzky,来自波士顿布利甘-妇女医院,以及 Dr. Stephan U. Schuele,来自埃文斯顿北方大学,认为睡眠时俯卧位姿势可能是癫痫患者猝死的危险因素这一发现意义重大。

“这意味着让患者采取仰卧位睡眠,正如预防SIDS所做的一样,可防止大量的猝死事件的发生,”他们补充道。“研究表明,简单的措施可能对预防癫痫患者猝死有很大的效果,照顾患者并改变俯卧位睡姿值得我们为此做出努力。”

原始出处:

Sleeping on stomach 'may raise risk of sudden death in epilepsy'MedicalNewsToday.Jan,24,2015

Jennifer A. Liebenthal,Shasha Wu,Sandra Rose,John S. Ebersole,James X. Tao.Association of prone position with sudden unexpected death in epilepsy.Neurology February 17, 2015 vol. 84 no. 7 703-709

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  1. [GetPortalCommentsPageByObjectIdResponse(id=40290, encodeId=2f87402909e, content=是啊,有什么机理, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Thu Oct 22 20:29:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999537, encodeId=f1be199953eae, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Feb 17 22:08:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32504, encodeId=24153250453, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun Jul 12 20:09:00 CST 2015, time=2015-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32201, encodeId=e0283220121, content=机理呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32202, encodeId=f0973220286, content=有待进一步学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=)]
    2015-10-22 三三五五

    是啊,有什么机理

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=40290, encodeId=2f87402909e, content=是啊,有什么机理, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Thu Oct 22 20:29:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999537, encodeId=f1be199953eae, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Feb 17 22:08:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32504, encodeId=24153250453, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun Jul 12 20:09:00 CST 2015, time=2015-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32201, encodeId=e0283220121, content=机理呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32202, encodeId=f0973220286, content=有待进一步学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=)]
    2016-02-17 yinhl1978
  3. [GetPortalCommentsPageByObjectIdResponse(id=40290, encodeId=2f87402909e, content=是啊,有什么机理, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Thu Oct 22 20:29:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999537, encodeId=f1be199953eae, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Feb 17 22:08:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32504, encodeId=24153250453, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun Jul 12 20:09:00 CST 2015, time=2015-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32201, encodeId=e0283220121, content=机理呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32202, encodeId=f0973220286, content=有待进一步学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=)]
    2015-07-12 huaxipanxing

    看看

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=40290, encodeId=2f87402909e, content=是啊,有什么机理, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Thu Oct 22 20:29:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999537, encodeId=f1be199953eae, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Feb 17 22:08:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32504, encodeId=24153250453, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun Jul 12 20:09:00 CST 2015, time=2015-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32201, encodeId=e0283220121, content=机理呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32202, encodeId=f0973220286, content=有待进一步学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=)]
    2015-07-10 保守主义

    机理呢?

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=40290, encodeId=2f87402909e, content=是啊,有什么机理, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Thu Oct 22 20:29:00 CST 2015, time=2015-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999537, encodeId=f1be199953eae, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Feb 17 22:08:00 CST 2016, time=2016-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32504, encodeId=24153250453, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun Jul 12 20:09:00 CST 2015, time=2015-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32201, encodeId=e0283220121, content=机理呢?, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=32202, encodeId=f0973220286, content=有待进一步学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d0f31631005, createdName=保守主义, createdTime=Fri Jul 10 07:53:00 CST 2015, time=2015-07-10, status=1, ipAttribution=)]
    2015-07-10 保守主义

    有待进一步学习

    0

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