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Circulation:夜间血压表型对心血管疾病风险的影响不容小觑

2020-11-10 星云 MedSci原创

动态家庭血压(BP)监测参数比办公室BP监测参数能更好地预测心血管事件,但是目前尚缺乏可靠的数据,也缺乏关于心力衰竭(HF)风险的信息。JAMP研究采用相同的BP监测设备、和方案在所有研究中心中评估夜

动态家庭血压(BP)监测参数比办公室BP监测参数能更好地预测血管事件,但是目前尚缺乏可靠的数据,也缺乏关于心力衰竭(HF)风险的信息。JAMP研究采用相同的BP监测设备、和方案在所有研究中心中评估夜间高血压和夜间BP变动模式与心血管事件(包括HF)发生之间的关系。

该研究纳入至少存在一个心血管风险因素的患者,多数为高血压。受试患者接受24小时动态BP监测。

最终分析纳入了6359位患者(68.6±11.7岁,48%男性)。中位随访了4.5±2.4年,共记录了306例心血管事件,包括119例卒中、99例冠心病,88例HF。夜间收缩压与动脉粥样硬化性心血管疾病和HF的风险显著相关(血压每升高20 mmHg,风险比[HR]分别是1.18和1.25)。与正常节律的患者相比,BP昼夜节律紊乱与总体心血管疾病风险增加有关(HR 1.48),特别是HF(HR 2.45)。

夜间BP水平和升高模式与总心血管事件发生率,特别是HF,独立相关。该研究结果揭示了针对夜间收缩压的降压策略的重要性。

原始出处:

Kazuomi Kario, et al. Nighttime Blood Pressure Phenotype and Cardiovascular Prognosis. Circulation. 2020;142:1810–1820

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    2020-11-12 tastas
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    2020-11-11 Psycho.Dr Du

    保证血压稳定,减少血压变异率#高血压#

    0

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    2020-11-10 ms4000000062793346

    学习学习

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