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Neurology:根据年龄、亚型、性别的年轻人卒中发病率和时间趋势

2019-04-25 xing.T 网络

由此可见,35岁以上的中年人卒中发病率随年龄增长而增加,18-44岁人群中,女性高于男性,在十年内增加了23%,并且是缺血性卒中增加为主。女性和男性的脑内出血发病率相当,并且随着时间的推移保持稳定。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,该研究旨在根据性别和年龄调查年轻人卒中及其亚型的发病率,并研究随时间推移的趋势。

研究人员通过链接国家登记处(出院、死因和人口登记)建立全国范围的队列,这些参与者为荷兰1998年至2010年间经 ICD-9 / ICD-10诊断的18-50岁患者和首次发生缺血性卒中、脑出血或未指定卒中的≥50岁患者。结局是按年龄、性别和卒中亚型分层的卒中的年发病率,其随时间的变化,以及18-50岁患者与≥50岁患者的发病率的比较。

研究人员确定了15257名患者(53%为女性;平均年龄为41.8岁)。发病率随着年龄呈指数增长(R2=0.99),女性高于男性,最年轻的患者(18-44岁)最突出。缺血性卒中的相对比例随年龄增长而增加(18-24岁:38.3%; 44-49岁:56.5%),而脑出血的相对比例下降(18-24岁:34.0%; 44-49岁:18.3%)。年轻人卒中发病率增加(1998年:14.0/100000人/年:2010年:17.2;23%; p<0.001),其中35岁以上人群和缺血性卒中发病率增加(46%),而发病率在≥50岁时下降(329.1%-292.2%; -11%; p=0.009)。

由此可见,35岁以上的中年人卒中发病率随年龄增长而增加,18-44岁人群中,女性高于男性,在十年内增加了23%,并且是缺血性卒中增加为主。女性和男性的脑内出血发病率相当,并且随着时间的推移保持稳定。 

原始出处:

Merel S. Ekker,et al.Stroke incidence in young adults according to age, subtype, sex, and time trends.Neurology.2019.https://doi.org/10.1212/WNL.0000000000007533

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    2019-10-12 yinhl1978
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    2019-05-12 用户被禁用

    感谢分享,学习了

    0

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    2019-04-25 1ddf0692m34(暂无匿称)

    学习了,谢谢分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2000758, encodeId=21272000e582b, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Sat Oct 12 11:01:00 CST 2019, time=2019-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1951602, encodeId=cf52195160203, content=<a href='/topic/show?id=53a5595e1dc' target=_blank style='color:#2F92EE;'>#时间趋势#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59571, encryptionId=53a5595e1dc, topicName=时间趋势)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Tue Feb 04 09:01:00 CST 2020, time=2020-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1823552, encodeId=7f2c1823552c1, content=<a href='/topic/show?id=b2873e9220e' target=_blank style='color:#2F92EE;'>#发病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37922, encryptionId=b2873e9220e, topicName=发病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Sun Nov 17 12:01:00 CST 2019, time=2019-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=366119, encodeId=b10a36611968, content=感谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/04/23/fa6ad39852b3fd26b8f7093d53c322a1.jpg, createdBy=807b5083691, createdName=用户被禁用, createdTime=Sun May 12 17:11:54 CST 2019, time=2019-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=365249, encodeId=e2623652496f, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Apr 25 19:01:10 CST 2019, time=2019-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026345, encodeId=07e0102634529, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Thu Apr 25 18:01:00 CST 2019, time=2019-04-25, status=1, ipAttribution=)]
    2019-04-25 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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