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J Clin Oncol:成年癌症幸存者心功能不全预防和监测

2017-05-22 常路 环球医学

心功能不全是某些针对癌症治疗的严重不良反应,或影响癌症患者的实际生存率。2017年3月,发表在《J Clin Oncol.》的一篇文章发布了成年癌症幸存者心功能不全的预防和监测新指南。目的:心功能不全是某些针对癌症治疗的严重不良反应,可干扰疗效,降低生活质量,或影响癌症患者的实际生存率。本研究的目的为制定出预防和监测成年发病癌症幸存者心功能不全的建议。方法:多学科专家小组通过Meta分析、随机临床

心功能不全是某些针对癌症治疗的严重不良反应,或影响癌症患者的实际生存率。2017年3月,发表在《J Clin Oncol.》的一篇文章发布了成年癌症幸存者心功能不全的预防和监测新指南。

目的:心功能不全是某些针对癌症治疗的严重不良反应,可干扰疗效,降低生活质量,或影响癌症患者的实际生存率。本研究的目的为制定出预防和监测成年发病癌症幸存者心功能不全的建议。

方法:多学科专家小组通过Meta分析、随机临床试验、观察性研究、临床经验的系统回顾(1996~2016)制定了建议。使用经过确立的方法按照研究设计评估研究质量。使用决策支持方法论指南部分制定指南建议。

结果:总共104项研究符合入组标准,成为撰写建议的证据基础。这些指南中的建议强度基于证据的质量、数量和一致性和获益和风险之间的平衡。

建议:风险足够高的个体开始治疗前,医疗提供者开始讨论心功能不全的潜力是重要的。某些较高风险的癌症幸存者人群可从针对癌症治疗期间实施的预防和筛查策略中获益。已经接受潜在的心脏毒性治疗的幸存者中,应高度临床怀疑心脏病,并且心脏评估阈值应较低。对于某些较高风险的癌症幸存者,完成针对癌症治疗后,需要使用心脏影像进行常规监测,以便可以开始合理的干预来阻止甚至逆转心功能不全的进展。

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    2017-08-03 minlingfeng
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    2017-05-23 ylzr123

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

    0

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    2017-05-23 luominglian113

    学习了,谢谢分享

    0

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