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Journal for ImmunoTherapy of Cancer:CTLA-4及OX40双特异性抗体ATOR-1015的临床前数据

2019-04-13 不详 网络

Alligator Bioscience公司近日宣布,CTLA-4及OX40双特异性抗体ATOR-1015的临床前数据已经发表在《Journal for ImmunoTherapy of Cancer》杂志上。

Alligator Bioscience公司近日宣布,CTLA-4OX40双特异性抗体ATOR-1015临床前数据已经发表在《Journal for ImmunoTherapy of Cancer》杂志上。已发表的数据显示,ATOR-1015在几种实验性肿瘤模型(包括膀胱癌,结肠癌胰腺癌)中具有抗肿瘤作用。此外,数据表明ATOR-1015PD-1阻断疗法的组合能够诱导长期免疫记忆以及增强的抗肿瘤反应。

该数据支持了ATOR-1015的持续临床开发,目前正在进行I期研究(NCT03782467),这项研究的结果预计将在2020年下半年公布。


原始出处:

http://www.firstwordpharma.com/node/1634983#axzz5kmtmGZrh

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    2019-04-15 hywen7328
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