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J Clin Periodontol:睡眠时间短,容易掉牙?!

2021-11-16 MedSci原创 MedSci原创

牙周病主要包括牙龈炎和牙周炎,发病率很高,在老年人群中更为严重。有明确的证据表明,牙周病与炎症标志物、心血管疾病和消化系统肿瘤有关。研究已证实睡眠时间短可导致多种不利的健康结果,同时睡眠短还会增加感染

牙周病主要包括牙龈炎和牙周炎,发病率很高,在老年人群中更为严重。有明确的证据表明,牙周病与炎症标志物、心血管疾病和消化系统肿瘤有关。研究已证实睡眠时间短可导致多种不利的健康结果,同时睡眠短还会增加感染发生的风险,并可能激活炎症信号通路。许多研究都报道了睡眠短与牙周病之间的关联,但结论并不一致。近日,发表于J Clin Periodontol的一项荟萃分析评估了睡眠时间短与牙周病(包括牙齿脱落和牙周炎)之间的关联。

研究人员检索了相关研究,采用反方差加权(IVW)法、加权中位数法、MR-Egger法和MR-Robust Adjusted Profile Score(RAPS)法进行MR分析,评估短时睡眠对牙齿脱落和牙周炎的因果关系。

结果,该项荟萃分析共纳入了7项横断面研究,包括40196人。分析结果显示,睡眠时间短和牙周病之间的关联没有统计学意义(几率(OR)=1.13,95%置信区间(CI):0.99,1.28;P = 0.076)。在MR分析中,研究人员并没有观察到由遗传决定的睡眠时间短与牙齿脱落(β:-0.056;95%CI:-0.181至0.068;P = 0.376)和牙周炎(β:-0.112;95%CI:-0.340至0.117;P = 0.339)之间存在统计学意义上的因果联系。

综上所述,该研究结果表明,根据目前的证据,睡眠时间短与牙周病(包括牙齿脱落和牙周炎)的风险没有统计学上的关联。未来的研究需要注意睡眠时间的测量,统计模型的选择,以及睡眠健康的其他相关领域。

 

原始出处:

 

Feixiang Zhou, et al., Association of short sleep with risk of periodontal disease: A meta-analysis and Mendelian randomization study. J Clin Periodontol. 2021 Aug;48(8):1076-1084. doi: 10.1111/jcpe.13483.  

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    2022-08-21 feather89
  2. [GetPortalCommentsPageByObjectIdResponse(id=1729193, encodeId=84861e291937d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Aug 21 06:24:24 CST 2022, time=2022-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070859, encodeId=955710e08591e, content=终于找到牙不好的原因了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=19253094654, createdName=570547476, createdTime=Tue Nov 16 19:07:41 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070749, encodeId=1bc310e07495a, content=好文章,值得学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJlfgys76DEiaNtbYo2re3ibjrUPTRibEXRyFwAB4aAGiave842S0FQDf0wAoaH226NiaSoPPDzhndsf1g/132, createdBy=88b489038, createdName=yangchou, createdTime=Tue Nov 16 12:42:49 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070732, encodeId=523410e073255, content=睡眠时间短容易掉牙, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1e05489924, createdName=ms1000002136354097, createdTime=Tue Nov 16 12:25:45 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070728, encodeId=c2f510e07287e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d785442816, createdName=ms8000000545763740, createdTime=Tue Nov 16 12:22:03 CST 2021, time=2021-11-16, status=1, ipAttribution=)]
    2021-11-16 570547476

    终于找到牙不好的原因了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1729193, encodeId=84861e291937d, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Aug 21 06:24:24 CST 2022, time=2022-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070859, encodeId=955710e08591e, content=终于找到牙不好的原因了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=19253094654, createdName=570547476, createdTime=Tue Nov 16 19:07:41 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070749, encodeId=1bc310e07495a, content=好文章,值得学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJlfgys76DEiaNtbYo2re3ibjrUPTRibEXRyFwAB4aAGiave842S0FQDf0wAoaH226NiaSoPPDzhndsf1g/132, createdBy=88b489038, createdName=yangchou, createdTime=Tue Nov 16 12:42:49 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070732, encodeId=523410e073255, content=睡眠时间短容易掉牙, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1e05489924, createdName=ms1000002136354097, createdTime=Tue Nov 16 12:25:45 CST 2021, time=2021-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1070728, encodeId=c2f510e07287e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0d785442816, createdName=ms8000000545763740, createdTime=Tue Nov 16 12:22:03 CST 2021, time=2021-11-16, status=1, ipAttribution=)]
    2021-11-16 yangchou

    好文章,值得学习。

    0

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    2021-11-16 ms1000002136354097

    睡眠时间短容易掉牙

    0

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    2021-11-16 ms8000000545763740

    学习了

    0

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