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PNAS:高度警惕!空气中花粉浓度越高,SARS-CoV-2感染率越高!

2021-03-10 MedSci原创 MedSci原创

春天的脚步悄悄的来临,又到了百花齐放的季节,然而对于花粉过敏的人来说,又是打喷嚏,流泪,鼻塞的时候。

春天的脚步悄悄的来临,又到了百花齐放的季节,然而对于花粉过敏的人来说,又是打喷嚏,流泪,鼻塞的时候。爱花人士也不要高兴的太早,近日,来自慕尼黑工业大学(TUM)的科研人员发现,空气中花粉浓度越高,SARS-CoV-2感染率越高。

为了研究花粉-病毒共同暴露的潜在影响,研究人员基于全球31个国家的248个空气花粉监测点进行了一个大型的横断面和纵向研究。在2020310日至14日间,在整个北半球,温暖的天气使得空气中花粉浓度(图2中用较大的圆圈表示),312日欧洲大陆较为明显。研究人员发现,这种现象刚好与SARS-CoV-2的高感染率相吻合(图2中用较深颜色的圆圈表示)。

为了明确人与人之间接触的影响,研究人员考虑了每个研究区域的人口密度,以及封锁效果,在所有可能的组合下:没有任何封锁,混合封锁-无封锁制度,以及完全封锁下。

研究人员发现,在某些情况下,空气中的花粉浓度与湿度和温度具有协同作用。在前4天花粉浓度较高后,感染率增加最为频繁。在没有封锁规定的时间间隔内,每立方米空气中每增加100粒花粉,感染率平均增加4%。在德国的一些城市,每天每立方米记录的花粉粒浓度高达500粒,导致感染率总体增加了20%以上。但是,在实行封锁规则的地区,在可比的花粉浓度下,平均感染率下降一半。

空气中的花粉会削弱免疫反应。花粉浓度高会导致呼吸道对病毒的免疫反应减弱,从而引起咳嗽和感冒。当病毒进入人体时,抗病毒干扰素的蛋白质会向附近的细胞发出信号,以增强其抗病毒防御能力,从而阻止入侵者。但是,如果空气中的花粉浓度很高,并且花粉颗粒被病毒颗粒吸入,则产生的抗病毒干扰素就会减少,有益的炎症反应本身也受到影响。因此,在花粉浓度高的日子里,可能导致呼吸道疾病的数量增加。值得注意的是,这与个人是否对不同的花粉类型过敏无关。

综上,地方性冠状病毒(OC43HKU1229ENL63株)以及其他常见呼吸道病毒(如呼吸道合胞病毒和A型流感)的感染在冬季或早春达到高峰。对于高危人群可以通过观察花粉预报和戴防尘口罩来保护自己。

原始出处

Athanasios Damialis et al. Higher airborne pollen concentrations correlated with increased SARS-CoV-2 infection rates, as evidenced from 31 countries across the globeProceedings of the National Academy of Sciences (2021). DOI: 10.1073/pnas.2019034118

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    2021-06-26 hukaixun
  2. 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    2021-04-16 drwjr
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    2021-04-07 gujun830412

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    0

  4. 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createdName=drwjr, createdTime=Fri Apr 16 21:29:40 CST 2021, time=2021-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=954677, encodeId=2a3b9546e77e, content=预防, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/10/f6f1f6ef2f0f4f5eb8d6b9f97243bb3f.jpg, createdBy=c5102133863, createdName=gujun830412, createdTime=Wed Apr 07 14:35:53 CST 2021, time=2021-04-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1321257, encodeId=a705132125ed4, content=<a href='/topic/show?id=ac0d159007f' target=_blank style='color:#2F92EE;'>#SARS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15900, encryptionId=ac0d159007f, topicName=SARS)], attachment=null, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/H3QXYibjbzM9C5GELMGhjqMatvmOsXy5gzoqIT6XJqYYCg7BqyfaLVW7gmk0bjAUJygFZUxt3XakaHUP7VIGDww/132, createdBy=a1285314326, createdName=taken110, createdTime=Wed Mar 10 22:44:28 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947254, encodeId=ebbc94e25465, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eSJU4KmCcksOucic5QWjmGQ9TC26lamwHOpicnuQEJ8CicgnB2gInMNMq16nDqPAM14icdO9V8fjsU17RibfGRVLCbQ/132, createdBy=4a442531103, createdName=梅斯@峰, createdTime=Wed Mar 10 22:15:29 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947252, encodeId=97d794e252eb, content=空气中花粉浓度越高,SARS-CoV-2感染率越高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Wed Mar 10 22:07:05 CST 2021, time=2021-03-10, status=1, ipAttribution=)]
    2021-03-12 小刀医生
  5. 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topicList=[TopicDto(id=65497, encryptionId=ac3d6549e75, topicName=浓度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=16b213663040, createdName=12498974m55暂无昵称, createdTime=Fri Mar 12 12:29:40 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947379, encodeId=c14a94e3793a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/58e01f5adcbf4aae90dfc25bd03c739f/1aca8d53476d43fca347e4819bda61f4.jpg, createdBy=b2d85436799, createdName=Lizhihua6, createdTime=Thu Mar 11 12:19:42 CST 2021, time=2021-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947266, encodeId=f91f94e2663a, content=花粉携带吗,看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Wed Mar 10 22:07:05 CST 2021, time=2021-03-10, status=1, ipAttribution=)]
  6. 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topicList=[TopicDto(id=65497, encryptionId=ac3d6549e75, topicName=浓度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=16b213663040, createdName=12498974m55暂无昵称, createdTime=Fri Mar 12 12:29:40 CST 2021, time=2021-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947379, encodeId=c14a94e3793a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201120/58e01f5adcbf4aae90dfc25bd03c739f/1aca8d53476d43fca347e4819bda61f4.jpg, createdBy=b2d85436799, createdName=Lizhihua6, createdTime=Thu Mar 11 12:19:42 CST 2021, time=2021-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947266, encodeId=f91f94e2663a, content=花粉携带吗,看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Wed Mar 10 22:07:05 CST 2021, time=2021-03-10, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1937991, encodeId=6915193e9912c, content=<a href='/topic/show?id=02de15902d3' target=_blank style='color:#2F92EE;'>#SARS-CoV#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=15902, encryptionId=02de15902d3, topicName=SARS-CoV)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Sat Jun 26 01:29:40 CST 2021, time=2021-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1856446, encodeId=2cf918564466e, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/H3QXYibjbzM9C5GELMGhjqMatvmOsXy5gzoqIT6XJqYYCg7BqyfaLVW7gmk0bjAUJygFZUxt3XakaHUP7VIGDww/132, createdBy=a1285314326, createdName=taken110, createdTime=Wed Mar 10 22:44:28 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947254, encodeId=ebbc94e25465, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eSJU4KmCcksOucic5QWjmGQ9TC26lamwHOpicnuQEJ8CicgnB2gInMNMq16nDqPAM14icdO9V8fjsU17RibfGRVLCbQ/132, createdBy=4a442531103, createdName=梅斯@峰, createdTime=Wed Mar 10 22:15:29 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947252, encodeId=97d794e252eb, content=空气中花粉浓度越高,SARS-CoV-2感染率越高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Wed Mar 10 22:07:05 CST 2021, time=2021-03-10, status=1, ipAttribution=)]
    2021-03-11 Lizhihua6

    学习了

    0

  8. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/H3QXYibjbzM9C5GELMGhjqMatvmOsXy5gzoqIT6XJqYYCg7BqyfaLVW7gmk0bjAUJygFZUxt3XakaHUP7VIGDww/132, createdBy=a1285314326, createdName=taken110, createdTime=Wed Mar 10 22:44:28 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947254, encodeId=ebbc94e25465, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eSJU4KmCcksOucic5QWjmGQ9TC26lamwHOpicnuQEJ8CicgnB2gInMNMq16nDqPAM14icdO9V8fjsU17RibfGRVLCbQ/132, createdBy=4a442531103, createdName=梅斯@峰, createdTime=Wed Mar 10 22:15:29 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947252, encodeId=97d794e252eb, content=空气中花粉浓度越高,SARS-CoV-2感染率越高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Wed Mar 10 22:07:05 CST 2021, time=2021-03-10, status=1, ipAttribution=)]
    2021-03-10 taken110

    花粉携带吗,看看

    0

  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Wed Mar 10 22:07:05 CST 2021, time=2021-03-10, status=1, ipAttribution=)]
    2021-03-10 梅斯@峰

    学习了

    0

  10. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/H3QXYibjbzM9C5GELMGhjqMatvmOsXy5gzoqIT6XJqYYCg7BqyfaLVW7gmk0bjAUJygFZUxt3XakaHUP7VIGDww/132, createdBy=a1285314326, createdName=taken110, createdTime=Wed Mar 10 22:44:28 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947254, encodeId=ebbc94e25465, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eSJU4KmCcksOucic5QWjmGQ9TC26lamwHOpicnuQEJ8CicgnB2gInMNMq16nDqPAM14icdO9V8fjsU17RibfGRVLCbQ/132, createdBy=4a442531103, createdName=梅斯@峰, createdTime=Wed Mar 10 22:15:29 CST 2021, time=2021-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=947252, encodeId=97d794e252eb, content=空气中花粉浓度越高,SARS-CoV-2感染率越高。, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4gCIdSaEkahCNuUWZv4iaKmqvUKHyKnBiarBM9RStQKBeV5Lh6GYYFiamdV5KlSfbLvmAgZTLtq81XA/0, createdBy=13511650672, createdName=言西早, createdTime=Wed Mar 10 22:07:05 CST 2021, time=2021-03-10, status=1, ipAttribution=)]
    2021-03-10 言西早

    空气中花粉浓度越高,SARS-CoV-2感染率越高。

    0

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艾草和葎草花粉在中国北方是2中最为重要的秋季过敏过敏原。在2001年的代表性数据表明了过敏性鼻炎总是领先或者是同时和中国北方的秋季花粉过敏病人哮喘发生。最近,有研究人员利用代表性的数据调查了血清特异性lgE (slgE)水平与葎草和/或艾草花粉的相关性,时间点事秋季花粉诱导的过敏性鼻炎患者哮喘开始时。研究包括了1096名秋季花粉病患者,并且进行了面对面交谈和对葎草和艾草的slgE测试,阐释和记录了

Int J Mol Sci :花粉蛋白酶再过敏性障碍中具有多重作用

过敏性疾病是世界范围内的一种重要的健康问题。花粉是过敏性鼻炎,结膜炎和哮喘的主要激发因子。花粉中释放的蛋白酶可能在典型的免疫和炎症响应中具有重要作用。

J Allergy Clin Immunol:天然花粉接触下过敏和不过敏受试者症状预测生物标记的确定

在敏感个体中,花粉接触能够诱导局部和系统过敏免疫响应,但是非敏感个体也接触花粉。花粉接触下的症状表达动力学还未有系统研究,尤其是在非过敏个体中。

Auris Medical宣布启动AM-301治疗过敏性鼻炎的临床研究

研究对象将在过敏原激发室暴露在花粉中4小时,评估暴露后患者的总鼻部症状评分(TNSS)(临床终点)。

Int Arch Allergy Immunol:儿童和青少年中桃树花粉和水蜜桃9敏感和过敏研究

尽管植物和水果花粉是虫媒的且和接触的工人有关,研究人员展示了在桃树栽培地区的成年人中,桃树花粉(PTP)和水蜜桃9(Pru 9)的致敏和诱导症状情况。研究人员在年龄为3-19岁的一个大的群体中研究了PTP和Pru9的致敏和临床相关向情况,并进行了详细的调查问卷和皮刺测试来调查相关的过敏原、PTP和Pru9,并通过鼻激发测试(NPT)和症状评分指数探究临床相关性情况。研究人员共评估了685名儿童(平

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