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Obesity:肥胖与超重会增加女性II型糖尿病的风险

2014-08-25 MedSci译 MedSci原创

肥胖对II型糖尿病增加,已有大量研究。但是它们之间关系有多大,需要大样本才能解释这一问题。最新一项研究波士顿Brigham and Women's Hospital研究人员发起一项研究,采用大样本登记数据库进一步阐述肥胖超重与女性II型糖尿病之间的关系,研究发表在最近的Obesity杂志上。研究人员采用共纳入两个登记数据库中的数据,其一为Nurses' Health Study (1984-200

肥胖对II型糖尿病增加,已有大量研究。但是它们之间关系有多大,需要大样本才能解释这一问题。最新一项研究波士顿Brigham and Women's Hospital研究人员发起一项研究,采用大样本登记数据库进一步阐述肥胖超重与女性II型糖尿病之间的关系,研究发表在最近的Obesity杂志上。

研究人员采用共纳入两个登记数据库中的数据,其一为Nurses' Health Study (1984-2008)数据库,共有61821位受试者,其二为Nurses' Health Study II (1991-2011)数据库,有63653位受试者。这些人群按BMI进行分为超重(BMI 25-30 kg m-2 )或肥胖 (BMI ≥ 30 kg m-2 )。采用COX回归模型研究超重,肥胖与II型糖尿病风险的关系。

研究发现,汇集这两个队列的数据库,超重每2年会增加9% (RR = 1.09, 95% CI 1.08-1.09)的糖尿病发生风险;对于肥胖而言,肥胖每2年会增加14% (RR = 1.14, 95% CI 1.14-1.15)的糖尿病发生风险。因此,超重和肥胖都可能增加女性II型糖尿病的风险.

原始出处:
Hu Y, Bhupathiraju SN, de Koning L, Hu FB.Duration of obesity and overweight and risk of type 2 diabetes among us women.Obesity (Silver Spring). 2014 Jul 31. doi: 10.1002/oby.20851.

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    2015-03-01 智慧医人
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    2015-04-11 x35042875

    糖尿病肾病进展风险的关系没有发现。

    0

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    2014-08-27 lingaifan
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    2014-08-27 skhzy

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