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JAHA:贫血的老年人卒中后死亡风险更高

2016-08-18 fsy 译 MedSci原创

根据美国心脏协会杂志的最新研究,美国心脏协会/美国卒中协会杂志的一项新的研究显示,贫血,缺乏红细胞,可能与患中风的老年人的死亡风险更高的风险有关。

美国心脏协会/美国卒中协会杂志的一项新的研究显示,贫血(由于缺乏红细胞)可能会增加老年卒中患者的死亡风险。

贫血是急性脑卒中患者常见的症状。贫血和低血红蛋白(红血细胞中携带氧气至整个身体的蛋白)水平在老年人中也很常见,苏格兰阿伯丁大学,医学博士,老年医学教授Phyo Myint说。

来自英国的研究人员考察了8013例住院患者的数据,患者的平均年龄77岁,这些患者在2003年至2015年期间因急性卒中入院。研究人员评估了在卒中入院直到一年过程中不同时间点,贫血和血红蛋白水平对死亡的影响。

研究人员发现,约四分之一的卒中患者在入院时存在贫血症状,不管是缺血性卒中(血管凝固),还是出血性卒中(血管破裂),在随访长达一年时,贫血都会增加死亡的风险。

此外,血红蛋白水平升高与预后较差和死亡风险较高有关,这主要出现在卒中后的第一个月内,这意味着低和高水平的血红蛋白都可能与卒中后死亡高风险相关联。

“我们发现,贫血的缺血性卒中患者死亡的可能性是无贫血患者的两倍,而出血性卒中的死亡风险高1.5倍左右,”Myint说。“所以,如果有人患卒中,并且还有贫血的症状,那么他的预后会更差。”

除了英国地区卒中注册,研究人员还系统地回顾了迄今发表的相关文献。他们使用了20项以前的研究来进行一次更大规模的研究,收集了来自众多国家的数据,研究人群增长到29943例卒中患者。研究人员说,这能更好的量化贫血的影响,并增加了研究结果的普遍性。

研究人员认为,这项研究强调了贫血对卒中结果的影响,以及需要增加对贫血的卒中患者的意识和干预措施。


“干预的一个例子是治疗贫血的根本原因,如缺铁,这也是在这个年龄组中比较常见的,”阿伯丁大学的合作者和医学生Raphae Barlas说。“该研究已令人信服地证明,贫血会加重卒中的结果,所以我们识别高危患者和优化管理是非常重要的。”

原始出处:

Raphae S. Barlas, Katie Honney, Yoon K. Loke,et al.Impact of Hemoglobin Levels and Anemia on Mortality in Acute Stroke: Analysis of UK Regional Registry Data, Systematic Review, and Meta‐Analysis. JAHA: Journal of the American Heart Association, 2016.8.18

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  2. [GetPortalCommentsPageByObjectIdResponse(id=1671259, encodeId=263016e12593a, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=131, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Sat Oct 01 23:00:00 CST 2016, time=2016-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=142174, encodeId=58b51421e402, content=学习了,文章有深度,值得探究。, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Oct 08 21:25:02 CST 2016, time=2016-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=109994, encodeId=4c8110999452, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sat Sep 03 00:04:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=104437, encodeId=6aba10443e1d, content=这篇资讯写的真好,带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Fri Aug 26 11:33:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1255584, encodeId=f7031255584c3, content=<a href='/topic/show?id=587f6339050' target=_blank style='color:#2F92EE;'>#死亡风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63390, encryptionId=587f6339050, topicName=死亡风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sat Aug 20 08:00:00 CST 2016, time=2016-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267319, encodeId=9a32126e31900, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Aug 20 08:00:00 CST 2016, time=2016-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=101185, encodeId=d370101185d7, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLMzGpMQ8w4I7FpiblCXNcmI6O7TDINutbaicEUpoYFR1rWqn3kTbulfMhT0iaPFurLz2ddEcWe3BiciaQ/0, createdBy=5f6e1724878, createdName=136****0753赵, createdTime=Fri Aug 19 22:58:00 CST 2016, time=2016-08-19, status=1, ipAttribution=)]
    2016-10-08 ylzr123

    学习了,文章有深度,值得探究。

    0

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    2016-09-03 李东泽

    很好,不错,以后会多学习

    0

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    2016-08-26 李东泽

    这篇资讯写的真好,带给我们新知识,启发新思维,不论是科研还是临床工作都有很大的帮助。。。

    0

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    2016-08-20 zhaohui6731
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    2016-08-19 136****0753赵

    值得学习

    0

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