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J Clin Periodontol:糖尿病前期以及控制良好的糖尿病与牙周病不存在相关关系

2015-04-09 MedSci MedSci原创

J Clin Periodontol:糖尿病前期以及控制良好的糖尿病与牙周病不存在相关关系关键词:糖尿病前期 糖尿病 牙周病 牙周炎 牙周附着丧失 无牙颌 高血糖 血糖紊乱 总所周知,糖尿病和牙周炎之间具有双向关系,牙周炎可以影响机体血糖控制,糖尿病又会影响机体的牙周状态。但是很少有研究关于糖尿病前期以及控制良好的糖尿病与牙周炎之间的关系。糖尿病前期是指介于糖尿病和正常血糖之间的一种状态,被认为是

总所周知,糖尿病和牙周炎之间具有双向关系,牙周炎可以影响机体血糖控制,糖尿病又会影响机体的牙周状态。但是很少有研究关于糖尿病前期以及控制良好的糖尿病与牙周炎之间的关系。糖尿病前期是指介于糖尿病和正常血糖之间的一种状态,被认为是糖尿病的必经阶段,是糖尿病的预警信号。具体说就是餐后血糖在7.8mmol/L到11.1mmol/L之间(即糖耐量低减),或空腹血糖在6.1mmol/L到7.0mmol/L之间(即空腹血糖受损)的状态。

德国的一项研究表明,糖尿病前期以及控制良好的糖尿病与牙周炎之间已无相关关系。该研究结果于2015年3月21日在线发表于JOURNAL OF CLINICAL PERIODONTOLOGY《临床牙周病杂志》。

该研究纳入了3086名(49.4%为男性,年龄在20-82岁)研究对象,采用横断面调查方法。随机评估研究对象的半口临床附着丧失(CAL)以及牙周探诊深度(PPD)的水平,确定每个研究对象的牙齿数目。糖尿病前期包括了空腹血糖和糖耐量的异常,控制良好的糖尿病的定义为糖化血红蛋白(HbA1c)<7.0%。研究对象被分成了以下几类:糖耐量正常(NGT),糖尿病前期,初诊2型糖尿病(T2DM),T2DM的HbA1c<7%,T2DM的HbA1c≥7%。

研究结果发现糖尿病前期与平均CAL、PPD及牙齿丧失数目(OR=1.09 (95%-CI: 0.69-1.71))或无牙颌(OR=0.96 (95%-CI: 0.75-1.22)都没有关系。控制良好的糖尿病患者的平均CAL以及无牙颌数目明显低于控制较差的糖尿病患者。该研究结果表明只有严重血糖紊乱的糖尿病状态与牙周炎的患病率以及牙齿丧失的数目相关。但是仍需要纵向研究来评估血糖控制良好的患者牙周状态的变化。

原始出处:
Kowall B, Holtfreter B, Völzke H, Schipf S, Mundt T, Rathmann W, Kocher T. Prediabetes  and well controlled diabetes are not associated with periodontal disease: the SHIP Trend Study.  J Clin Periodontol. 2015 Mar 21. doi: 10.1111/jcpe.12391. 

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    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

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  3. [GetPortalCommentsPageByObjectIdResponse(id=125362, encodeId=f4d512536245, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:30:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998446, encodeId=2294199844654, content=<a href='/topic/show?id=a14ce2526b3' target=_blank style='color:#2F92EE;'>#相关关系#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72526, encryptionId=a14ce2526b3, topicName=相关关系)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e183245, createdName=Eleven11, createdTime=Sat Dec 26 22:54:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725801, encodeId=fac11e2580182, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Apr 26 00:54:00 CST 2015, time=2015-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20308, encodeId=5f0a2030834, content=AKI对心衰临床治疗意义重大,但依然需要研究检验其适用性, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 22:37:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282226, encodeId=88b5128222633, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Sat Apr 11 09:54:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450402, encodeId=03b614504023e, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Sat Apr 11 09:54:00 CST 2015, time=2015-04-11, status=1, ipAttribution=)]
    2015-04-26 feather89
  4. [GetPortalCommentsPageByObjectIdResponse(id=125362, encodeId=f4d512536245, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 14:30:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1998446, encodeId=2294199844654, content=<a href='/topic/show?id=a14ce2526b3' target=_blank style='color:#2F92EE;'>#相关关系#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72526, encryptionId=a14ce2526b3, topicName=相关关系)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e183245, createdName=Eleven11, createdTime=Sat Dec 26 22:54:00 CST 2015, time=2015-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725801, encodeId=fac11e2580182, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Sun Apr 26 00:54:00 CST 2015, time=2015-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=20308, encodeId=5f0a2030834, content=AKI对心衰临床治疗意义重大,但依然需要研究检验其适用性, beContent=null, objectType=article, channel=null, level=null, likeNumber=173, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150920/IMG55FDE671A89482379.jpg, createdBy=cef3108336, createdName=x35042875, createdTime=Sat Apr 11 22:37:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282226, encodeId=88b5128222633, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Sat Apr 11 09:54:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450402, encodeId=03b614504023e, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Sat Apr 11 09:54:00 CST 2015, time=2015-04-11, status=1, ipAttribution=)]
    2015-04-11 x35042875

    AKI对心衰临床治疗意义重大,但依然需要研究检验其适用性

    0

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