Lung Cancer：PET/CT评价肺癌纵膈淋巴结转移作用有限

2014-05-22 佚名 dxy

肺腺癌和鳞癌是最常见的非小细胞肺癌，对其的合理治疗需要准确的临床分期。纵膈镜检查目前仍被认为是确定纵膈淋巴结状态的金标准，但很多发展中国家并未常规性进行该项检查。非侵入性检查方法中，CT检查因主要基于淋巴结大小不够精确。18F-FDG PET/CT检查对于评价直径<15mm的淋巴结可能具有一定意义。针对这种情况，中国哈医大肿瘤医院的Yu医生等进行了一项回顾性研究，发现18F-FDG PE

肺腺癌和鳞癌是最常见的非小细胞肺癌，对其的合理治疗需要准确的临床分期。纵膈镜检查目前仍被认为是确定纵膈淋巴结状态的金标准，但很多发展中国家并未常规性进行该项检查。非侵入性检查方法中，CT检查因主要基于淋巴结大小不够精确。18F-FDG PET/CT检查对于评价直径<15mm的淋巴结可能具有一定意义。【原文下载】

针对这种情况，中国哈医大肿瘤医院的Yu医生等进行了一项回顾性研究，发现18F-FDG PET/CT对腺/鳞癌直径<15mm的淋巴结的评价作用有限，且在鳞癌中假阳性率较高，考虑CT的衰减性有助于提高准确性。文章发表在2014年5月的Lung Cancer上。

该回顾性研究纳入了2005年10月至2012年10月间术前接受18F-FDG PET/CT检查且伴有直径<15mm纵膈淋巴结的116例腺癌和234例鳞癌患者，所有患者随后进行了病理检查确诊，对比PET/CT与病理检查结果间的差异。

研究结果显示，PET/CT检查在腺癌组中的特异性和准确性较鳞癌组高。与PET相比，PET/CT对鳞癌组有着更高的特异性和准确性，对腺癌组有着更高的特异性、准确性和阳性预测值。

原始出处

Lu P1, Sun Y2, Sun Y1, Yu L3.The role of 18F-FDG PET/CT for evaluation of metastatic mediastinal lymph nodes in patients with lung squamous-cell carcinoma or adenocarcinoma.Lung Cancer. 2014 Apr 18.【原文下载】

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2015-03-31 feather89

#PE#

80 0
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2014-05-24 sodoo

#淋巴结#

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2014-05-24 snf701207

#淋巴结转移#

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2014-05-24 chaojitidian

#PET/CT#

99 0
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2014-05-24 ms7514935887898259

#PET#

109 0
[GetPortalCommentsPageByObjectIdResponse(id=1725610, encodeId=e78f1e25610fd, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Mar 31 20:21:00 CST 2015, time=2015-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1292949, encodeId=625f1292949ba, content=<a href='/topic/show?id=df626600877' target=_blank style='color:#2F92EE;'>#淋巴结#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66008, encryptionId=df626600877, topicName=淋巴结)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6cc1239, createdName=sodoo, createdTime=Sat May 24 02:21:00 CST 2014, time=2014-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1302490, encodeId=022a130249098, content=<a href='/topic/show?id=7be06602886' target=_blank style='color:#2F92EE;'>#淋巴结转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66028, encryptionId=7be06602886, topicName=淋巴结转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25e7304, createdName=snf701207, createdTime=Sat May 24 02:21:00 CST 2014, time=2014-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309663, encodeId=c9a41309663d3, content=<a href='/topic/show?id=412114080d1' target=_blank style='color:#2F92EE;'>#PET/CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14080, encryptionId=412114080d1, topicName=PET/CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Sat May 24 02:21:00 CST 2014, time=2014-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331025, encodeId=8b15133102541, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Sat May 24 02:21:00 CST 2014, time=2014-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1444092, encodeId=f169144409295, content=<a href='/topic/show?id=3d9291459d1' target=_blank style='color:#2F92EE;'>#评价#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91459, encryptionId=3d9291459d1, topicName=评价)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1fee5134542, createdName=huagfeg, createdTime=Sat May 24 02:21:00 CST 2014, time=2014-05-24, status=1, ipAttribution=)]
2014-05-24 huagfeg

#评价#

85 0

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