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世界首例抗衰老药将临床试验 或让人活到120岁

2016-06-07 佚名 参考消息网

英媒称,世界首例抗衰老药将于明年进行临床试验,试验结果可能让阿尔茨海默症和帕金森病等疾病成为遥远的回忆。 英国《每日电讯报》网站12月1日报道称,科学家现在相信,延缓人的衰老速度并让他们健康活到110多岁、甚至120多岁是有可能的。 尽管这听起来或许像科幻小说,但研究人员已证明,用于治疗糖尿病的二甲双胍可以延长动物的寿命。美国食品和药物管理局现在已批准该项临床试验,以验证这种药物是否能对人产生

英媒称,世界首例抗衰老药将于明年进行临床试验,试验结果可能让阿尔茨海默症和帕金森病等疾病成为遥远的回忆。

英国《每日电讯报》网站12月1日报道称,科学家现在相信,延缓人的衰老速度并让他们健康活到110多岁、甚至120多岁是有可能的。

尽管这听起来或许像科幻小说,但研究人员已证明,用于治疗糖尿病二甲双胍可以延长动物的寿命。美国食品和药物管理局现在已批准该项临床试验,以验证这种药物是否能对人产生同样的效果。

如果试验成功,则意味着70多岁的老者从生物学角度而言将和50多岁的人一样健康。这可能会为老年学开启一个新时代。届时医生将不必再分别治疗癌症、糖尿病和痴呆症,而只需针对衰老这一根本的机制进行治疗。

苏格兰抗衰老专家、就职于美国加利福尼亚的巴克老龄化问题研究所的戈登·利思戈教授是上述研究的顾问之一。他说:“如果你把衰老过程作为研究对象,并且延缓了衰老,那么你就同样延缓了所有与衰老相关的疾病。这是革命性的,是前所未有的。”

衰老并非生命所不可避免的组成部分,因为所有细胞内都含有一种可让机体永远正常工作的DNA蓝图。有些海洋生物根本就不会衰老。

但在我们的一生中,必须要经历数十亿次的细胞分裂,才能维持机体的正常运转。而细胞分裂次数越多,就会有更多的错误潜入这一进程。随着细胞问题的增多,机体最终将无法对损伤进行修复。以癌症为例,细胞不再有能力摆脱突变,肿瘤也就不断发展。再以阿尔茨海默症为例,大脑一旦停止清理淀粉样斑块,人随后便会出现痴呆症状。

科学家认为,最好的抗衰老候选药物是二甲双胍。它是世界上应用最广泛的降糖药,服用它每天仅需花费10便士(约合15美分)。

二甲双胍能增加向细胞中释放的氧分子数量,这似乎能增加机体的强健程度并延长寿命。

当比利时研究人员在秀丽隐杆线虫身上进行二甲双胍测试时,这些线虫不仅衰老速度变慢,而且保持更健康状态的时间也变长了。它们的活动速度没有减慢,也没有长出皱纹。对老鼠使用二甲双胍后,它们的寿命延长了近40%,骨骼也变得更结实。去年,英国加的夫大学发现,糖尿病患者服用二甲双胍后,他们事实上比非糖尿病患者的寿命更长,尽管理论上糖尿病应该让他们平均减寿8年。

这项名为“用二甲双胍对抗衰老”的临床试验计划于明年冬天在美国开始。目前,来自多家机构的科学家正在筹集资金并招募3000名年龄在70岁到80岁之间、患有或今后有可能患有癌症、心脏病和痴呆症的老年人。他们期待能借此证明,二甲双胍能延缓衰老并阻止疾病的发生与发展。

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    2016-09-17 ylzr123

    赞一个!好文章拜读了,认真学习了。

    0

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    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1968441, encodeId=46541968441bc, content=<a href='/topic/show?id=a57f208660f' target=_blank style='color:#2F92EE;'>#世界首例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20866, encryptionId=a57f208660f, topicName=世界首例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Wed Jan 18 20:26:00 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129095, encodeId=76201290955b, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Sep 17 08:20:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122329, encodeId=c3e212232938, content=己拜读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 10:02:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119404, encodeId=f31711940467, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 15:42:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92605, encodeId=c6259260551, content=120岁,估计到时候**率就明显高了吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sun Jul 10 19:30:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89019, encodeId=32f58901904, content=确实看到了一丝希望,但得做好最坏打算。, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/4A00E77B913D12376371C3D34B9E6937/100, createdBy=23961732752, createdName=QQ3821412e, createdTime=Wed Jun 08 09:02:00 CST 2016, time=2016-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88962, encodeId=002288962aa, content=副作用是什么?_?, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Tue Jun 07 16:52:00 CST 2016, time=2016-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88958, encodeId=d61188958bc, content=这个可喜可忧, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b3781729882, createdName=WEIXINa82df6bc, createdTime=Tue Jun 07 16:15:00 CST 2016, time=2016-06-07, status=1, ipAttribution=)]
    2016-09-10 1e10c84am36(暂无匿称)

    好文章,百姓也能从中学到好多医学知识

    0

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    2016-07-10 oo902

    120岁,估计到时候**率就明显高了吧

    0

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    2016-06-08 QQ3821412e

    确实看到了一丝希望,但得做好最坏打算。

    0

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    2016-06-07 lyh994

    副作用是什么?_?

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1968441, encodeId=46541968441bc, content=<a href='/topic/show?id=a57f208660f' target=_blank style='color:#2F92EE;'>#世界首例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20866, encryptionId=a57f208660f, topicName=世界首例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=917c196, createdName=sjzlzc007, createdTime=Wed Jan 18 20:26:00 CST 2017, time=2017-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=129095, encodeId=76201290955b, content=赞一个!好文章拜读了,认真学习了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Sep 17 08:20:00 CST 2016, time=2016-09-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122329, encodeId=c3e212232938, content=己拜读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 10:02:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=119404, encodeId=f31711940467, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Sep 10 15:42:00 CST 2016, time=2016-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92605, encodeId=c6259260551, content=120岁,估计到时候**率就明显高了吧, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sun Jul 10 19:30:00 CST 2016, time=2016-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=89019, encodeId=32f58901904, content=确实看到了一丝希望,但得做好最坏打算。, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/4A00E77B913D12376371C3D34B9E6937/100, createdBy=23961732752, createdName=QQ3821412e, createdTime=Wed Jun 08 09:02:00 CST 2016, time=2016-06-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88962, encodeId=002288962aa, content=副作用是什么?_?, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/24/1c2dbd6706e64df33befd6663f1d6b37.jpg, createdBy=94f61661779, createdName=lyh994, createdTime=Tue Jun 07 16:52:00 CST 2016, time=2016-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=88958, encodeId=d61188958bc, content=这个可喜可忧, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b3781729882, createdName=WEIXINa82df6bc, createdTime=Tue Jun 07 16:15:00 CST 2016, time=2016-06-07, status=1, ipAttribution=)]
    2016-06-07 WEIXINa82df6bc

    这个可喜可忧

    0

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