Baidu
map

JCEM:血清SP-D升高或能提示肥胖2型糖尿病患者出现了肺部受累

2017-09-29 MedSci MedSci原创

糖尿病时长期存在的高血糖,导致各种组织,特别是眼、肾、心脏、血管、神经的慢性损害、功能障碍。而肺功能损害是糖尿病晚期并发症的新靶点。生物标记物可能有助于鉴别患者是否需要进行功能性呼吸试验。因此,来自西班牙的研究人员探讨了血清表面活性蛋白D(SP-D)和血清表面活性蛋白A(SP-A)是否能作为既往没有肺部病变的肥胖2型糖尿病患者,出现肺损伤时的有效生物标志物。这是一项在肥胖门诊进行的病例对照研究。研

糖尿病时长期存在的高血糖,导致各种组织,特别是眼、肾、心脏、血管、神经的慢性损害、功能障碍。

而肺功能损害是糖尿病晚期并发症的新靶点。生物标记物可能有助于鉴别患者是否需要进行功能性呼吸试验。因此,来自西班牙的研究人员探讨了血清表面活性蛋白D(SP-D)和血清表面活性蛋白A(SP-A)是否能作为既往没有肺部病变的肥胖2型糖尿病患者,出现肺损伤时的有效生物标志物。

这是一项在肥胖门诊进行的病例对照研究。研究对象为49例肥胖2型糖尿病患者和根据年龄、性别、BMI和腰围匹配的98例非糖尿病患者。研究人员采用酶联免疫吸附测定法测定血清SP-D和SP-A。研究人员评估了他们的用力肺活量和静态肺容量。

研究人员发现,T2D患者的血清SP-D浓度比对照组高(P = 0.006)。两组间的血清SP-A浓度无差异。一秒用力呼气容积(FEV1)与血清SP-D之间呈负相关(R = -0.265,P = 0.029),而血清SP-D和余气量之间存在显著的正相关(r = 0.293,P = 0.043)。从受试者操作特性分析,确定预期FEV1<80%的最佳SP-D临界值为132.3ng/mL(曲线下面积为0.725,灵敏度77.7%,特异性69.4%)。多元逐步回归分析显示血清SP-D≥132.3ng/mL 与预期FEV1<80%独立相关(R2 = 0.406)。在所有亚组中,只有2型糖尿病的存在与血清SP-D变异独立相关(R2 = 0.138)。

研究人员认为,临床医务工作者可以考虑将血清SP-D作为检测肥胖2型糖尿病患者肺损害的有效生物标志物

原始出处:

López-Cano C, Lecube A,et al.Serum Surfactant Protein D as a Biomarker for Measuring Lung Involvement in Obese Type 2 Diabetic Patients.J Clin Endocrinol Metab. 2017 Sep 13. doi: 10.1210/jc.2017-00913. [Epub ahead of print]

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1777668, encodeId=76c21e77668b9, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Jan 16 15:29:00 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794249, encodeId=8d021e94249bb, content=<a href='/topic/show?id=9a21165e332' target=_blank style='color:#2F92EE;'>#SP-D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16573, encryptionId=9a21165e332, topicName=SP-D)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c950224, createdName=hjwang79, createdTime=Sat May 12 02:29:00 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774483, encodeId=72741e7448371, content=<a href='/topic/show?id=483e8233ecd' target=_blank style='color:#2F92EE;'>#肺部受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82337, encryptionId=483e8233ecd, topicName=肺部受累)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d7338549832, createdName=wrj0134, createdTime=Mon Oct 23 02:29:00 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063050, encodeId=a276206305019, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sat Jun 09 07:29:00 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383346, encodeId=839913833467e, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474304, encodeId=deac14e43040d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248958, encodeId=35dc2489581e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Sep 30 01:33:32 CST 2017, time=2017-09-30, status=1, ipAttribution=)]
    2018-01-16 smallant2015
  2. [GetPortalCommentsPageByObjectIdResponse(id=1777668, encodeId=76c21e77668b9, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Jan 16 15:29:00 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794249, encodeId=8d021e94249bb, content=<a href='/topic/show?id=9a21165e332' target=_blank style='color:#2F92EE;'>#SP-D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16573, encryptionId=9a21165e332, topicName=SP-D)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c950224, createdName=hjwang79, createdTime=Sat May 12 02:29:00 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774483, encodeId=72741e7448371, content=<a href='/topic/show?id=483e8233ecd' target=_blank style='color:#2F92EE;'>#肺部受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82337, encryptionId=483e8233ecd, topicName=肺部受累)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d7338549832, createdName=wrj0134, createdTime=Mon Oct 23 02:29:00 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063050, encodeId=a276206305019, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sat Jun 09 07:29:00 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383346, encodeId=839913833467e, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474304, encodeId=deac14e43040d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248958, encodeId=35dc2489581e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Sep 30 01:33:32 CST 2017, time=2017-09-30, status=1, ipAttribution=)]
    2018-05-12 hjwang79
  3. [GetPortalCommentsPageByObjectIdResponse(id=1777668, encodeId=76c21e77668b9, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Jan 16 15:29:00 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794249, encodeId=8d021e94249bb, content=<a href='/topic/show?id=9a21165e332' target=_blank style='color:#2F92EE;'>#SP-D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16573, encryptionId=9a21165e332, topicName=SP-D)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c950224, createdName=hjwang79, createdTime=Sat May 12 02:29:00 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774483, encodeId=72741e7448371, content=<a href='/topic/show?id=483e8233ecd' target=_blank style='color:#2F92EE;'>#肺部受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82337, encryptionId=483e8233ecd, topicName=肺部受累)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d7338549832, createdName=wrj0134, createdTime=Mon Oct 23 02:29:00 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063050, encodeId=a276206305019, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sat Jun 09 07:29:00 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383346, encodeId=839913833467e, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474304, encodeId=deac14e43040d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248958, encodeId=35dc2489581e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Sep 30 01:33:32 CST 2017, time=2017-09-30, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1777668, encodeId=76c21e77668b9, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Jan 16 15:29:00 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794249, encodeId=8d021e94249bb, content=<a href='/topic/show?id=9a21165e332' target=_blank style='color:#2F92EE;'>#SP-D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16573, encryptionId=9a21165e332, topicName=SP-D)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c950224, createdName=hjwang79, createdTime=Sat May 12 02:29:00 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774483, encodeId=72741e7448371, content=<a href='/topic/show?id=483e8233ecd' target=_blank style='color:#2F92EE;'>#肺部受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82337, encryptionId=483e8233ecd, topicName=肺部受累)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d7338549832, createdName=wrj0134, createdTime=Mon Oct 23 02:29:00 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063050, encodeId=a276206305019, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sat Jun 09 07:29:00 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383346, encodeId=839913833467e, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474304, encodeId=deac14e43040d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248958, encodeId=35dc2489581e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Sep 30 01:33:32 CST 2017, time=2017-09-30, status=1, ipAttribution=)]
    2018-06-09 achengzhao
  5. [GetPortalCommentsPageByObjectIdResponse(id=1777668, encodeId=76c21e77668b9, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Jan 16 15:29:00 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794249, encodeId=8d021e94249bb, content=<a href='/topic/show?id=9a21165e332' target=_blank style='color:#2F92EE;'>#SP-D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16573, encryptionId=9a21165e332, topicName=SP-D)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c950224, createdName=hjwang79, createdTime=Sat May 12 02:29:00 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774483, encodeId=72741e7448371, content=<a href='/topic/show?id=483e8233ecd' target=_blank style='color:#2F92EE;'>#肺部受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82337, encryptionId=483e8233ecd, topicName=肺部受累)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d7338549832, createdName=wrj0134, createdTime=Mon Oct 23 02:29:00 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063050, encodeId=a276206305019, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sat Jun 09 07:29:00 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383346, encodeId=839913833467e, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474304, encodeId=deac14e43040d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248958, encodeId=35dc2489581e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Sep 30 01:33:32 CST 2017, time=2017-09-30, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1777668, encodeId=76c21e77668b9, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Jan 16 15:29:00 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794249, encodeId=8d021e94249bb, content=<a href='/topic/show?id=9a21165e332' target=_blank style='color:#2F92EE;'>#SP-D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16573, encryptionId=9a21165e332, topicName=SP-D)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c950224, createdName=hjwang79, createdTime=Sat May 12 02:29:00 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774483, encodeId=72741e7448371, content=<a href='/topic/show?id=483e8233ecd' target=_blank style='color:#2F92EE;'>#肺部受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82337, encryptionId=483e8233ecd, topicName=肺部受累)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d7338549832, createdName=wrj0134, createdTime=Mon Oct 23 02:29:00 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063050, encodeId=a276206305019, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sat Jun 09 07:29:00 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383346, encodeId=839913833467e, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474304, encodeId=deac14e43040d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248958, encodeId=35dc2489581e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Sep 30 01:33:32 CST 2017, time=2017-09-30, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1777668, encodeId=76c21e77668b9, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Tue Jan 16 15:29:00 CST 2018, time=2018-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1794249, encodeId=8d021e94249bb, content=<a href='/topic/show?id=9a21165e332' target=_blank style='color:#2F92EE;'>#SP-D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16573, encryptionId=9a21165e332, topicName=SP-D)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c950224, createdName=hjwang79, createdTime=Sat May 12 02:29:00 CST 2018, time=2018-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1774483, encodeId=72741e7448371, content=<a href='/topic/show?id=483e8233ecd' target=_blank style='color:#2F92EE;'>#肺部受累#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82337, encryptionId=483e8233ecd, topicName=肺部受累)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d7338549832, createdName=wrj0134, createdTime=Mon Oct 23 02:29:00 CST 2017, time=2017-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063050, encodeId=a276206305019, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Sat Jun 09 07:29:00 CST 2018, time=2018-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383346, encodeId=839913833467e, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474304, encodeId=deac14e43040d, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sun Oct 01 07:29:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248958, encodeId=35dc2489581e, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Sat Sep 30 01:33:32 CST 2017, time=2017-09-30, status=1, ipAttribution=)]
    2017-09-30 yfjms

    学习了

    0

相关资讯

出现10个症状,你离糖尿病可能只有一步之遥!及早发现还不晚!

糖尿病可以说是一种非常让人痛苦的慢性病,这也不能吃,那也不能吃,而且还会导致各种并发症。其实在转化成糖尿之前,身体也会出现各种各样的症状,如果能够及时调整,或许还可以逆转!1明明吃很多,体重却在下降体重在不知不觉中下降,这其实是一种危险信号,如果没有刻意去减肥,每个月的体重却减少4-5公斤的话,这就说明身体肯定存在问题。专家表示:“如果饮食正常体重却在下降,很可能是患上了糖尿病。”糖尿病会促进血糖

JACC:2型糖尿病患者的心超分型

2型糖尿病(T2DM)能影响患者的心脏结构和功能,但是高血压、肥胖或者高龄同样可以引起相似的改变。近日,在国际心血管权威杂志JACC上发表了一篇旨在通过聚类分析将T2DM患者的心脏表型与临床预后联系在一起的临床研究。本研究纳入了842例T2DM患者,并对其基础的超声心动图特点和复合终点事件(心源性死亡率和住院率)进行评估。最终,共将患者分成了3个聚类。第一类患者拥有最低的左室质量分数和二尖瓣早期流

Neurology:老年糖尿病患者服用二甲双胍可降低痴呆风险

研究认为,对于75岁以下的II糖尿病患者,服用二甲双胍相比于磺脲类药物可降低患者的痴呆风险

 SCI TRANSL MED :糖尿病神经疼痛的“根源”已确定,患者再也不用忍受痛苦

伦敦国王学院的一项新研究揭示了,糖尿病患者慢性神经疼痛的分子基础,研究结果发表在《科学转化医学》杂志中,在报告中,研究人员确定了神经痛的目标,为治疗找到了目标。

诺和诺德新一代基础胰岛素Tresiba获CFDA批准

糖尿病巨头诺和诺德(Novo Nordisk)近日宣布,中国食品和药品监督管理总局(CFDA)已批准Tresiba(insulin degludec,德谷胰岛素)用于中国1型糖尿病(T1D)患者和2型糖尿病(T2D)患者的治疗。Tresiba是一种新一代、每日皮下注射一次的基础胰岛素,具有超长的药效持续时间,可在全天任何时间给药,这赋予了患者日常给药的灵活性。诺和诺德表示,将在2018年第一季度将

糖尿病不可忽视的并发症:胃轻瘫

糖尿病胃轻瘫(diabetic gastroparesis, DGP)是指糖尿病患者在没有机械性梗阻的情况下出现的胃延迟排空综合征, 常伴有餐后饱胀、恶心、呕吐、腹胀、食欲下降等症状。大约5% ~ 12% 的糖尿病患者伴有胃轻瘫,且女性患者多于男性,虽然没有足够证据显示该病能使患者寿命缩短, 但重度胃轻瘫可导致患者血糖难以控制,药物吸收受影响,甚至会出现低血糖、营养不良、电解质紊乱等情况,不仅给患

Baidu
map
Baidu
map
Baidu
map