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NEJM:呼吸道乳头状瘤病-病例报道

2019-07-25 xing.T MedSci原创

组织学检查发现鳞状乳头状瘤,其表面上皮细胞发生中度异常增生,并且在聚合酶链反应试验中检测到11型人乳头瘤病毒,诊断为呼吸道乳头状瘤病。该患者接受了激光辅助机械切除术,他的症状大量减轻。

患者为一名63岁的男性,因干咳和劳力性呼吸困难恶化3个月到呼吸科就诊。他有人类免疫缺陷病毒感染史,并且间歇性地接受了规定的抗逆转录病毒治疗数年。

该患者CD4计数为每立方毫米81个细胞。在肺部听诊时可听到明显的呼气喘息。胸部计算机断层扫描显示多处突出到气管腔和左右主干支气管中的病变。支气管镜检查结果发现气管后壁和左右主干支气管上有许多无柄、易碎、疣状病变。



组织学检查发现鳞状乳头状瘤,其表面上皮细胞发生中度异常增生,并且在聚合酶链反应试验中检测到11型人乳头瘤病毒,诊断为呼吸道乳头状瘤病。该患者接受了激光辅助机械切除术,他的症状大量减轻。

在7个月后的随访中,该患者的CD4计数增加到每立方毫米171个细胞。他症状有所复发,并进一步切除了复发性乳头状瘤。 

原始出处:

Nicola Dentale,et al.Respiratory Papillomatosis.N Engl J Med 2019;https://www.nejm.org/doi/full/10.1056/NEJMicm1816077

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    2019-07-26 zhmscau
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    2019-07-25 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2045017, encodeId=d065204501ed6, content=<a href='/topic/show?id=a4d02358610' target=_blank style='color:#2F92EE;'>#乳头状#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23586, encryptionId=a4d02358610, topicName=乳头状)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce5632, createdName=jianjun66, createdTime=Fri Jan 17 02:43:00 CST 2020, time=2020-01-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282492, encodeId=a17612824921a, content=<a href='/topic/show?id=700239e0772' target=_blank style='color:#2F92EE;'>#呼吸道#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39707, encryptionId=700239e0772, topicName=呼吸道)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2e94174, createdName=zhmscau, createdTime=Fri Jul 26 22:43:00 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1034893, encodeId=dcd01034893f2, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Jul 25 10:43:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370237, encodeId=91a53e0237f9, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Thu Jul 25 08:48:41 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 龙胆草

    学习谢谢分享

    0

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