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J Periodontol:系统牙周治疗对于高血压前期牙周炎患者血压及内皮微粒的影响:一项随机对照试验

2017-08-11 MedSci MedSci原创

目前,虽然一些研究显示牙周炎与血压(BP)升高之间存在正相关关系。但对于未进行任何抗高血压治疗牙周炎患者,系统牙周治疗对BP水平下降和内皮微粒(EMP)的影响的研究仍缺乏。因此,本临床试验探讨了系统牙周治疗是否会降低高血压前期牙周炎的患者的血压水平和EMP。

目前,虽然一些研究显示牙周炎与血压(BP)升高之间存在正相关关系。但对于未进行任何抗高血压治疗牙周炎患者,系统牙周治疗对BP水平下降和内皮微粒(EMP)的影响的研究仍缺乏。因此,本临床试验探讨了系统牙周治疗是否会降低高血压前期牙周炎的患者的血压水平和EMP。实验纳入107例患者, 95例完成试验,将病人随机分组(47例为对照治疗组,48例为强化治疗组)。患者接受连续4周的治疗,随访6个月。在治疗前和治疗后1,3和6个月评估BP和EMP的水平。结果:经过牙周治疗6个月后牙周病变明显改善(P <0.05)。同时,IT组与CT组相比,收缩压,舒张压和EMPs明显降低(绝对差:分别为12.57和9.65 mm Hg, 581.59 /μL;95%置信区间:10.45-14.69, 7.06-12.24,和348.12-815.06; P <0.05)。 BP水平和EMP的降低与探诊深度的改善有关(皮尔森积分相关性,分别为r = 0.358,0.336和0.676; P = 0.009,0.008,P <0.001)。根据作者的最新知识,本研究首次证明无需进行任何抗高血压药物治

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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232517, encodeId=b09923251e54, content=本研究首次证明无需进行任何抗高血压药物治疗,系统牙周治疗可能是降低高血压前期牙周炎患者BP和EMP水平的有效手段。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Aug 11 19:18:12 CST 2017, time=2017-08-11, status=1, ipAttribution=)]
    2018-02-26 feather89
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    2018-01-08 amyloid
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  4. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232517, encodeId=b09923251e54, content=本研究首次证明无需进行任何抗高血压药物治疗,系统牙周治疗可能是降低高血压前期牙周炎患者BP和EMP水平的有效手段。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Aug 11 19:18:12 CST 2017, time=2017-08-11, status=1, ipAttribution=)]
    2017-08-11 清风拂面

    谢谢分享,学习了

    0

  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232517, encodeId=b09923251e54, content=本研究首次证明无需进行任何抗高血压药物治疗,系统牙周治疗可能是降低高血压前期牙周炎患者BP和EMP水平的有效手段。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Aug 11 19:18:12 CST 2017, time=2017-08-11, status=1, ipAttribution=)]
    2017-08-11 惠映实验室

    学习了,谢谢。

    0

  10. 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channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102662, encryptionId=ead91026621c, topicName=高血压前期)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1448837648, createdName=kord1985, createdTime=Sun Aug 13 09:18:00 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1493496, encodeId=2f34149349625, content=<a href='/topic/show?id=dc4c6e51457' target=_blank style='color:#2F92EE;'>#牙周治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67514, encryptionId=dc4c6e51457, topicName=牙周治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=dc259064725, createdName=cooco, createdTime=Sun Aug 13 09:18:00 CST 2017, time=2017-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232557, encodeId=32ad23255ecb, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Fri Aug 11 20:36:42 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232552, encodeId=4c3f23255272, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Fri Aug 11 20:19:00 CST 2017, time=2017-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232517, encodeId=b09923251e54, content=本研究首次证明无需进行任何抗高血压药物治疗,系统牙周治疗可能是降低高血压前期牙周炎患者BP和EMP水平的有效手段。, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Aug 11 19:18:12 CST 2017, time=2017-08-11, status=1, ipAttribution=)]
    2017-08-11 有备才能无患

    本研究首次证明无需进行任何抗高血压药物治疗,系统牙周治疗可能是降低高血压前期牙周炎患者BP和EMP水平的有效手段。

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