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Diabetes Care:饮用咖啡可降低2型糖尿病风险

2014-04-29 desperado-c 丁香园

以前的荟萃分析表明咖啡摄入量与2型糖尿病风险呈负相关。然而,从那以后又有新的研究比较含咖啡因咖啡和无咖啡因咖啡与2型糖尿病风险关系,因此,需要对饮用咖啡与2型糖尿病风险的荟萃分析进行更新。 为此,来自美国哈佛大学公共卫生学院营养科的Frank B Hu教授及其团队进行一项研究,对已发表的比较饮用咖啡与2型糖尿病风险关系研究进行荟萃分析。该研究结果发表在2014年02月的Diabetes care

以前的荟萃分析表明咖啡摄入量与2型糖尿病风险呈负相关。然而,从那以后又有新的研究比较含咖啡因咖啡和无咖啡因咖啡与2型糖尿病风险关系,因此,需要对饮用咖啡与2型糖尿病风险的荟萃分析进行更新。

为此,来自美国哈佛大学公共卫生学院营养科的Frank B Hu教授及其团队进行一项研究,对已发表的比较饮用咖啡与2型糖尿病风险关系研究进行荟萃分析。该研究结果发表在2014年02月的Diabetes care杂志上。

该研究中,Frank B Hu教授等系统检索了PubMed和Embase数据库,选择评估饮用咖啡与2型糖尿病风险关系的队列研究或巢式病例对照研究,检索期限为1966年至2013年02月。使用限制性三次样条随机效应模型比较咖啡摄入量与2型糖尿病分析的关系。

最终,共有28项前瞻性研究入选,包括1109272例受试者和45335例2型糖尿病病例。随访周期从10月到20年不等。与从未饮用咖啡或极少饮用咖啡的受试者相比,每天饮用咖啡1到6杯的受试者糖尿病相对风险为0.92、0.85、0.79、0.75、0.71和0.67。每天多饮用一杯含咖啡因咖啡和无咖啡因咖啡,糖尿病相对风险分别为0.91和0.94。

该研究提示,饮用咖啡与2型糖尿病风险呈负相关,且两者存在剂量反应关系。不论是含咖啡因咖啡,还是无咖啡因咖啡都可降低糖尿病风险。

原始出处:


Ding M1, Bhupathiraju SN, Chen M, van Dam RM, Hu FB.Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis.Diabetes Care. 2014 Feb;37(2):569-86. doi: 10.2337/dc13-1203.

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    2014-09-17 智智灵药
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 咖啡和自杀似乎风马牛不相及,而一项新近发表于《生物精神病学》(World J Biol Psychiatry 2013 Jul 2)的研究却将两者紧紧联系在了一起。该研究显示,每天饮用数杯咖啡可使自杀风险降低50%,且男女性均适用。该研究旨在评估美国三个大规模队列中使用咖啡及咖啡因与自杀率的关系。来自哈佛大学的研究者获取了来自卫生专业人士随访研究项目 (HPFS,1988–2008)的

JACC:咖啡的心血管效应(下)

研究要点(下): 1.适当饮用咖啡可降低中风风险。 2.饮用咖啡可降低心血管疾病及中风死亡率 3.咖啡可降低抑郁症风险,并有助于保持体重。 4.很多个体饮用咖啡之后会出现心悸、焦虑、发抖和失眠等不良反应,此外,饮用咖啡可加快钙质流失,因此饮用咖啡人群应注意补充钙质。 5.常规饮用咖啡可造成个体依赖,但并不属于药物成瘾。 【原文下载】 饮用咖啡可降低心血管疾病及中风死亡率 

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