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J Periodontol:牙周骨缺损再生治疗后的长期稳定性:回顾性病例系列

2017-06-26 MedSci MedSci原创

本研究旨在评估牙周骨缺损(IBD)后再生治疗组织附着的长期稳定性。

本研究旨在评估牙周骨缺损(IBD)后再生治疗组织附着的长期稳定性。

实验对2004年至2010年期间至少接受一次IBD再生治疗的所有患者进行回顾性病例系列筛查。如果患者在术前和手术后12个月完成检查(菌班/牙龈指数,探诊深度[PD],临床垂直附着水平[CAL-V])),术后60±12个月需要进行复诊检查。复查包括检测白细胞介素(IL)-1多态性和牙周支持治疗(SPT)访视次数。实验共纳入41例患者(男24例,女17例,年龄中位数:62.0岁,下/上四分位数:49.8 / 68.3岁; 6例吸烟者,9例IL-1阳性),每个患者都有一处IBD。

结果:再生治疗1年(中位数:-3mm,下/上四分位数:-1.5 / -4mm; P <0.001)和5年(中位数:-3mm,下/上四分位数-1.9 /4.5 mm; P <0.001)均有显着地附着增加。实验未能检测出手术后1~5年的CAL-V中位数变化(中位数:0 mm;下/上四分位数:-1 / 1.5 mm; P = 0.84)。多元回归分析表明,术后1~5年SPT访视次数与CAL-V增加相关。 5年复查时,IL-1多态性和PD> 6 mm位点的百分比与手术后1~5年的CAL-V丧失相关。

结论:IBD通过再生治疗实现的CAL-V可能在5年内保持稳定。频繁的SPT有助于稳定性, IL-1多态性和广泛再感染与稳定性差有关。

原始出处:

Katrin Nickles, Bettina Dannewitz, Kerstin Gallenbach, et al. Long-Term Stability After Regenerative Treatment of Infrabony Defects: A Retrospective Case Series. Journal of Periodontology. 2017 June. doi: 10.1902/jop.2017.160704
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    2018-02-05 feather89
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    2017-06-28 lfcmxl
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