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J Clin Peiodontol:口腔健康与胃肠道癌症相关关系的研究

2020-06-24 网络 网络

口腔卫生不良与菌血症和全身性炎症密切相关,而菌血症和全身性炎症可以促进癌症的发生发展。本研究旨在分析口腔卫生指标与胃肠道癌风险之间的关系。

口腔卫生不良与菌血症和全身性炎症密切相关,而菌血症和全身性炎症可以促进癌症的发生发展。本研究旨在分析口腔卫生指标与胃肠道癌风险之间的关系。

本研究调查了来自韩国国家健康筛查队列的150774名受试者的数据进行的。根据牙周病和口腔卫生指标分析了胃肠道癌的发生:刷牙次数,牙科就诊,专业的牙齿清洁以及牙齿缺失的数量。根据国际疾病分类International Statistical Classification of Diseases10 codes C15–C26对胃肠道癌症进行分类

结果发现,在平均11.6年的随访中,胃肠道癌的10年发生率约为6.76%。在多变量分析中,在调整年龄,性别,收入水平,规律运动,饮酒,吸烟状况,体重指数,合并症史,收缩压和实验室检查结果之后,频繁刷牙(≥3/天)与胃肠道癌的风险降低之间有统计学意义(hazard ratio:0.91,95%置信区间(0.86-0.96),p <.001,p for trend <.001)。

因此,本实验可以推断,良好的口腔卫生习惯,尤其是经常刷牙,可以降低胃肠道癌的风险。

原文出处:

Kijeong Lee,Oral health and gastrointestinal cancer: A nationwide cohort study. Journal of Clinical Periodontology,2020 June, doi: 10.1111/jcpe.13304.

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