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BMJ:饮食与心脏病及中风风险研究(EPIC-Oxford研究)

2019-09-05 MedSci MedSci原创

研究发现,鱼食者和素食者缺血性心脏病风险低于肉食者,但出血和中风风险增加

近日研究人员探讨了饮食与缺血性心脏病和中风的关系。

EPIC-Oxford研究在1993年至2001年英国招募参与者,48188名没有缺血性心脏病、中风或心绞痛(或心血管疾病)病史的受试者被分为三个不同的饮食组:肉食者(食用肉类的受试者,无论他们是否食用鱼、奶制品或鸡蛋;n=24428)、鱼食者(食用鱼但没有肉;n=7506)以及素食者(n=16254)。研究的主要终点为缺血性心脏病和中风的事件病例( 包括缺血性和出血类型),直到 2016 年。

随访18.1年,共收治缺血性心脏病2820例,全脑卒中1072例,其中缺血性脑卒中519例,出血性脑卒中300例。经社会人口学和生活方式混杂因素校正后,食鱼者和素食者的缺血性心脏病患病率分别比食肉者低13%(HR:0.87)和22%(0.78,异质性p<0.001)。这一差异相当于,每1000素食主义者患缺血性心脏病的病例比肉食者少10例。自我报告的高胆固醇高血压糖尿病和体重指数调整后,缺血性心脏病的相关性部分减弱(HR: 0.90)。相比之下,素食者的总中风发生率(HR:1.20)比肉食者高20%,相当于每1000人中中风患者增加3例,主要是由于出血性中风导致的。在进一步调整疾病风险因素后,中风的关联性没有减弱。

研究发现,鱼食者和素食者缺血性心脏病风险低于肉食者,但出血和中风风险增加。

原始出处:


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    2019-11-17 gaoxiaoe
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    2019-09-05 guging

    中风是俗称,应该称为缺血性卒中吧

    0

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    2019-09-05 一个字-牛

    学习了谢谢分享

    0

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