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BMJ:还在妄想通过补钙预防骨折吗?

2015-10-02 Mechront 译 MedSci原创

补钙并不能有效预防骨折,不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。

市面上有一个观点经久不衰,骨质疏松补钙呗,预防骨折后补钙呗。其实从逻辑上来件并没有错,缺什么补什么,然后一定就能补到位,补到大家都想要的结果吗?近期有研究者对于这个经验性观点,进行了系统回顾。以探究补钙究竟能不能预防骨折,达到大家心中所想目的。

研究者检索了2013-07至2014-09间Ovid Medline, Embase, PubMed等数据库,以及系统回顾相关参考文献中关于补钙与骨折的研究。纳入了年龄> 50岁,通过膳食钙、牛奶或乳制品的摄入,或补钙剂(单独或联合VD)补钙,对研究对象骨折风险影响的相关文献。纳入文章中关于饮食补钙有2篇随机对照试验(n=262),44篇队列研究共计50次试验,涉及膳食钙(n = 37)、牛奶(n = 14)、或奶制品摄入补钙(n = 8)与骨折风险的探究。

研究结果显示,大多数研究报道膳食钙摄入和骨折风险之间没有联系(14/22全身骨折, 17/21髋部骨折, 7/8脊椎骨折, 5/7 前臂骨折);大多数研究报道也没有发现牛奶(25/28)和奶制品的摄入补钙(11/13)可以减少骨折风险,预防骨折。在26个随机对照试验中,数据表明补钙剂可以减少全身骨折风险(20次研究, n=58 573; RR 0.89, 95% CI 0.81 to 0.96),减少脊柱骨折风险(12 次研究, n=48 967.;RR 0.86, 95% CI 0.74 to 1.00),但是不减少髋部骨折风险(13 次研究, n=56 648; RR 0.95, 95% CI  0.76 to 1.18),也不减少前臂骨折风险(8次研究, n=51 775;RR  0.96, 95% CI  0.85 to 1.09)。不过研究组通过漏斗图和Egger's回归检验发现补钙剂与骨折风险研究存在发表偏倚。在随机对照试验中偏倚最小的(4次研究, n=44 505)试验表明, 补钙剂与骨折风险间没有统计学以及的联系,不管补钙剂有没有添加VD。只有在一个对虚弱的老年妇女(低膳食钙摄入量和低维生素D浓度)的试验发现,补钙剂可以显著减少骨折的风险。

研究结果表明,补钙并不能有效预防骨折,不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。


这项研究结果与BMJ另一项研究结果的结论相似:BMJ:补钙只能小幅度增加骨密度(META分析),这种极小幅度的骨密度增加,可能不足以预防骨折的发生。

原始出处:

Bolland MJ, Leung W, Tai V, Bastin S, Gamble GD, Grey A, et al. Calcium intake and risk of fracture: systematic review. Bmj. 2015;351:h4580.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1847715, encodeId=8cc9184e7150f, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Aug 16 10:52:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60198, encodeId=38ae6019875, content=应该普及这一认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=209, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:22:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60196, encodeId=88d96019693, content=实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60197, encodeId=6c6a6019e39, content=不错,赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38792, encodeId=e6bf38e9273, content=bmj的meta!, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150707/IMG559BDBCBCA5618647.jpg, createdBy=494c1631012, createdName=文刀, createdTime=Mon Oct 12 22:01:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38321, encodeId=fee3383219a, content=好文章,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 11 11:36:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38241, encodeId=adca382417a, content=值得好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150625/IMG558B8C995D7262168.jpg, createdBy=36ad1623080, createdName=cyzj007, createdTime=Fri Oct 09 07:01:00 CST 2015, time=2015-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38237, encodeId=f72c3823efc, content=不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Thu Oct 08 23:18:00 CST 2015, time=2015-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37675, encodeId=bc8d3e675a5, content=我是骨科医生,很喜欢med的骨科板块,从科普到高端都有, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 04 01:57:00 CST 2015, time=2015-10-04, status=1, ipAttribution=)]
    2016-08-16 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1847715, encodeId=8cc9184e7150f, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Aug 16 10:52:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60198, encodeId=38ae6019875, content=应该普及这一认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=209, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:22:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60196, encodeId=88d96019693, content=实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60197, encodeId=6c6a6019e39, content=不错,赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38792, encodeId=e6bf38e9273, content=bmj的meta!, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150707/IMG559BDBCBCA5618647.jpg, createdBy=494c1631012, createdName=文刀, createdTime=Mon Oct 12 22:01:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38321, encodeId=fee3383219a, content=好文章,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 11 11:36:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38241, encodeId=adca382417a, content=值得好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150625/IMG558B8C995D7262168.jpg, createdBy=36ad1623080, createdName=cyzj007, createdTime=Fri Oct 09 07:01:00 CST 2015, time=2015-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38237, encodeId=f72c3823efc, content=不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Thu Oct 08 23:18:00 CST 2015, time=2015-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37675, encodeId=bc8d3e675a5, content=我是骨科医生,很喜欢med的骨科板块,从科普到高端都有, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 04 01:57:00 CST 2015, time=2015-10-04, status=1, ipAttribution=)]
    2016-01-27 doctording1

    应该普及这一认识

    0

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    2016-01-27 doctording1

    实用

    0

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    2016-01-27 doctording1

    不错,赞一个

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1847715, encodeId=8cc9184e7150f, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Aug 16 10:52:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60198, encodeId=38ae6019875, content=应该普及这一认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=209, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:22:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60196, encodeId=88d96019693, content=实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60197, encodeId=6c6a6019e39, content=不错,赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38792, encodeId=e6bf38e9273, content=bmj的meta!, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150707/IMG559BDBCBCA5618647.jpg, createdBy=494c1631012, createdName=文刀, createdTime=Mon Oct 12 22:01:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38321, encodeId=fee3383219a, content=好文章,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 11 11:36:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38241, encodeId=adca382417a, content=值得好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150625/IMG558B8C995D7262168.jpg, createdBy=36ad1623080, createdName=cyzj007, createdTime=Fri Oct 09 07:01:00 CST 2015, time=2015-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38237, encodeId=f72c3823efc, content=不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Thu Oct 08 23:18:00 CST 2015, time=2015-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37675, encodeId=bc8d3e675a5, content=我是骨科医生,很喜欢med的骨科板块,从科普到高端都有, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 04 01:57:00 CST 2015, time=2015-10-04, status=1, ipAttribution=)]
    2015-10-12 文刀

    bmj的meta!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1847715, encodeId=8cc9184e7150f, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Aug 16 10:52:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60198, encodeId=38ae6019875, content=应该普及这一认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=209, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:22:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60196, encodeId=88d96019693, content=实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60197, encodeId=6c6a6019e39, content=不错,赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38792, encodeId=e6bf38e9273, content=bmj的meta!, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150707/IMG559BDBCBCA5618647.jpg, createdBy=494c1631012, createdName=文刀, createdTime=Mon Oct 12 22:01:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38321, encodeId=fee3383219a, content=好文章,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 11 11:36:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38241, encodeId=adca382417a, content=值得好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150625/IMG558B8C995D7262168.jpg, createdBy=36ad1623080, createdName=cyzj007, createdTime=Fri Oct 09 07:01:00 CST 2015, time=2015-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38237, encodeId=f72c3823efc, content=不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Thu Oct 08 23:18:00 CST 2015, time=2015-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37675, encodeId=bc8d3e675a5, content=我是骨科医生,很喜欢med的骨科板块,从科普到高端都有, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 04 01:57:00 CST 2015, time=2015-10-04, status=1, ipAttribution=)]
    2015-10-11 Bobby7868

    好文章,赞一个!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1847715, encodeId=8cc9184e7150f, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Aug 16 10:52:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60198, encodeId=38ae6019875, content=应该普及这一认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=209, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:22:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60196, encodeId=88d96019693, content=实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60197, encodeId=6c6a6019e39, content=不错,赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38792, encodeId=e6bf38e9273, content=bmj的meta!, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150707/IMG559BDBCBCA5618647.jpg, createdBy=494c1631012, createdName=文刀, createdTime=Mon Oct 12 22:01:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38321, encodeId=fee3383219a, content=好文章,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 11 11:36:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38241, encodeId=adca382417a, content=值得好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150625/IMG558B8C995D7262168.jpg, createdBy=36ad1623080, createdName=cyzj007, createdTime=Fri Oct 09 07:01:00 CST 2015, time=2015-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38237, encodeId=f72c3823efc, content=不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Thu Oct 08 23:18:00 CST 2015, time=2015-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37675, encodeId=bc8d3e675a5, content=我是骨科医生,很喜欢med的骨科板块,从科普到高端都有, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 04 01:57:00 CST 2015, time=2015-10-04, status=1, ipAttribution=)]
    2015-10-09 cyzj007

    值得好好看看

    0

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    2015-10-08 zhouxue1990

    不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1847715, encodeId=8cc9184e7150f, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Aug 16 10:52:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60198, encodeId=38ae6019875, content=应该普及这一认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=209, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:22:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60196, encodeId=88d96019693, content=实用, beContent=null, objectType=article, channel=null, level=null, likeNumber=127, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60197, encodeId=6c6a6019e39, content=不错,赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Wed Jan 27 00:21:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38792, encodeId=e6bf38e9273, content=bmj的meta!, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150707/IMG559BDBCBCA5618647.jpg, createdBy=494c1631012, createdName=文刀, createdTime=Mon Oct 12 22:01:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38321, encodeId=fee3383219a, content=好文章,赞一个!, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 11 11:36:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38241, encodeId=adca382417a, content=值得好好看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150625/IMG558B8C995D7262168.jpg, createdBy=36ad1623080, createdName=cyzj007, createdTime=Fri Oct 09 07:01:00 CST 2015, time=2015-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38237, encodeId=f72c3823efc, content=不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a1a01625167, createdName=zhouxue1990, createdTime=Thu Oct 08 23:18:00 CST 2015, time=2015-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37675, encodeId=bc8d3e675a5, content=我是骨科医生,很喜欢med的骨科板块,从科普到高端都有, beContent=null, objectType=article, channel=null, level=null, likeNumber=143, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=75bb1617091, createdName=Bobby7868, createdTime=Sun Oct 04 01:57:00 CST 2015, time=2015-10-04, status=1, ipAttribution=)]
    2015-10-04 Bobby7868

    我是骨科医生,很喜欢med的骨科板块,从科普到高端都有

    0

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