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盘点:8月14日BMJ研究精选

2017-08-19 zhangfan MedSci原创

BMJ

8月14日BMJ研究精选



【1】封面文章——NICE指南综述早产儿的护理


早产,定义为在37周之前出生,与新生儿的长短期风险相关。虽然大多数早产儿出生后有良好的发育和生活质量,但某些新生儿存在学习、功能、活动和参与性方面的问题。

统计发现,英格兰以及威尔士约7.5%的新生儿是早产儿,其中0.4%为极度早产。2015年约有53209名早产儿以及3014名极度早产儿出生。

近日NICE公布了新的早产儿儿童和青少年发展随访指南,旨在改进早产儿发育问题和疾病的早期诊断方法并提示相关风险因素。

指南提示:

1、早产儿发育相关疾病风险增加,并且风险随着胎龄的降低而增加;

2、对于30+0至36+0之间出生的早产儿,应强化新生儿医疗服务至2岁以降低早产相关疾病的风险;

3、对于28+0周之前的极度早产儿其患病风险极高,对极度早产儿的相关监控和随访应持续至4岁,并加强父母的教育;

4、任何阶段出现发育问题或疾病,应及时与父母以及二级医疗机构进行沟通,尽快进行治疗干预;

5、在任何阶段出现任何问题,应鼓励父母和照顾早产儿的家长与他们的全科医生交流。

【2】中低收入国家早产儿风险


近日研究人员评估了14个中低收入国家新生儿早产发生率和死亡率。

2012年,14个中低收入国家共2330万早产儿,约占新生儿总数的19.3%,其中1070万出生体重不足2500g。606500名新生儿死亡的原因是小胎龄,占所有新生儿死亡的21.9%。新生儿早产以及死亡最严重的地区为南亚,其发生率为34%,死亡率为26%。

【3】早产儿与神经系统疾病


近日研究人员考察了法国早产儿2年的神经发育结果并与1997年调查结果进行了比较。

5170名早产儿参与,其中22-26周早产儿2年的生存率为51.7%;27-31周2年生存率为93.1%;32-34周早产儿的2年生存率为98.6%,只有1名22-23周的早产儿幸存,对81%的患儿进行了脑瘫评价,其中24-26周,27-31周以及32-34周早产儿的发病率分别为 6.9% , 4.3% 以及1.0%。24-26周,27-31周以及32-34周早产儿神经系统发育异常率分别为50.2%, 40.7%以及36.2%。25-26周早产儿无严重或中度的运动或感觉障碍的生存率由45.5%上升至62.3%;22-24周早产儿的变化不大,32-34周早产儿生存率变化不显著但脑瘫发生率显著降低。

【4】成人社区获得性肺炎的原因及治疗进展


社区性肺炎仍然一种严重的疾病,通常患者的病因不明且治疗多数为经验性的。CT和MRI的应用增加了肺炎临床诊断的准确性,流行病学研究加强了社区获得性肺炎致病因素的认识,特别是加强了病毒性病原体的认知和发现。过去几十年中,由于不适当抗生素使用,耐甲氧西林金黄色葡萄球菌和抗生素耐药的革兰阴性菌导致的肺炎发病率不断提高。医药界对社区肺炎的治疗仍存在较大争议,特别是对于非常虚弱的病人。常见的方法包括抗生素和皮质类固醇的联合治疗。目前肺炎护理已得到了显著改善。目前普遍认为社区肺炎不仅仅是一种单一的急性肺病,更是一种急性和长期,涉及心脏和呼吸等多个系统的并发症。

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    2018-04-04 gaoxiaoe
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    2017-09-07 1de3b290m83(暂无匿称)

    关爱早产儿

    0

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    2017-08-23 1e11f6a6m77(暂无匿称)

    学习了.很有价值

    0

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    2017-08-20 meiliwuxian

    非常不错

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1848368, encodeId=5fe71848368b8, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Apr 04 14:59:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241537, encodeId=e0c124153efd, content=关爱早产儿, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Thu Sep 07 21:43:49 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236354, encodeId=594f236354af, content=学习了.很有价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf3f1954203, createdName=1e11f6a6m77(暂无匿称), createdTime=Wed Aug 23 12:15:01 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235273, encodeId=24042352e36a, content=非常不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Aug 20 06:54:16 CST 2017, time=2017-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235204, encodeId=d203235204c4, content=早产儿,存在多种风险, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/C3426ED027FF661B0C576A5B3127C2E8/40, createdBy=39dc1706090, createdName=QQ25ed180f, createdTime=Sun Aug 20 00:12:53 CST 2017, time=2017-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235185, encodeId=f17223518516, content=谢谢每期的总结, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM5dnicvDOticughRdDibueiaibRzxp5icvQ7EXr3aSxIIfpGFlQ/0, createdBy=e3031710362, createdName=tomoyo89, createdTime=Sat Aug 19 22:23:05 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235115, encodeId=07362351159d, content=写的很有价值很有深度, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Sat Aug 19 14:25:12 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235065, encodeId=a21e2350654a, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Aug 19 10:24:23 CST 2017, time=2017-08-19, status=1, ipAttribution=)]
    2017-08-20 QQ25ed180f

    早产儿,存在多种风险

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1848368, encodeId=5fe71848368b8, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Apr 04 14:59:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241537, encodeId=e0c124153efd, content=关爱早产儿, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Thu Sep 07 21:43:49 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236354, encodeId=594f236354af, content=学习了.很有价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf3f1954203, createdName=1e11f6a6m77(暂无匿称), createdTime=Wed Aug 23 12:15:01 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235273, encodeId=24042352e36a, content=非常不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Aug 20 06:54:16 CST 2017, time=2017-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235204, encodeId=d203235204c4, content=早产儿,存在多种风险, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/C3426ED027FF661B0C576A5B3127C2E8/40, createdBy=39dc1706090, createdName=QQ25ed180f, createdTime=Sun Aug 20 00:12:53 CST 2017, time=2017-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235185, encodeId=f17223518516, content=谢谢每期的总结, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM5dnicvDOticughRdDibueiaibRzxp5icvQ7EXr3aSxIIfpGFlQ/0, createdBy=e3031710362, createdName=tomoyo89, createdTime=Sat Aug 19 22:23:05 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235115, encodeId=07362351159d, content=写的很有价值很有深度, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Sat Aug 19 14:25:12 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235065, encodeId=a21e2350654a, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Aug 19 10:24:23 CST 2017, time=2017-08-19, status=1, ipAttribution=)]
    2017-08-19 tomoyo89

    谢谢每期的总结

    0

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    2017-08-19 Guoxj3234

    写的很有价值很有深度

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1848368, encodeId=5fe71848368b8, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Wed Apr 04 14:59:00 CST 2018, time=2018-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241537, encodeId=e0c124153efd, content=关爱早产儿, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Thu Sep 07 21:43:49 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236354, encodeId=594f236354af, content=学习了.很有价值, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf3f1954203, createdName=1e11f6a6m77(暂无匿称), createdTime=Wed Aug 23 12:15:01 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235273, encodeId=24042352e36a, content=非常不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Aug 20 06:54:16 CST 2017, time=2017-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235204, encodeId=d203235204c4, content=早产儿,存在多种风险, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://q.qlogo.cn/qqapp/1103841572/C3426ED027FF661B0C576A5B3127C2E8/40, createdBy=39dc1706090, createdName=QQ25ed180f, createdTime=Sun Aug 20 00:12:53 CST 2017, time=2017-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235185, encodeId=f17223518516, content=谢谢每期的总结, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmhead/Q3auHgzwzM5dnicvDOticughRdDibueiaibRzxp5icvQ7EXr3aSxIIfpGFlQ/0, createdBy=e3031710362, createdName=tomoyo89, createdTime=Sat Aug 19 22:23:05 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235115, encodeId=07362351159d, content=写的很有价值很有深度, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Sat Aug 19 14:25:12 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235065, encodeId=a21e2350654a, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Aug 19 10:24:23 CST 2017, time=2017-08-19, status=1, ipAttribution=)]
    2017-08-19 惠映实验室

    学习了,谢谢。

    0

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8月第1期BMJ研究精选

快速一览:近期BMJ病例报道汇总

【1】 BMJ:一例甲中部营养不良-案例报道  这是一名56岁男性,这名患者每个指甲的中央出现甲横嵴,并且指甲角质层缺失,双手拇指最明显(如图1所示),病史有10年。这三个特征是甲中部营养不良的特征,是甲床反复损伤的结果。损伤发生的可能机制,另一手指反复按压指甲角质层,致使指甲甲床损伤,角质层缺失。了解疾病潜在的机制,对甲床进行保护,治疗上应用石膏可能就足够了。【2】BMJ:易被误诊

The BMJ:医生警告,整粒葡萄可致幼儿窒息

医生在Archives of Disease in Childhood 杂志中警告,当食用整粒葡萄时幼儿可能会窒息死亡。英国阿伯丁皇家医院急诊科的Amy Lumsden 和Jamie Cooper 描述了3例在食用整粒葡萄后到急诊科抢救的幼儿病例,其中2例死亡。他们呼吁更多的公众意识到幼儿因食用葡萄而窒息的风险,并且建议幼儿在进食时应有成人监护。他们还敦促苏格兰和英国政府在食物标签中标明

盘点:7月第3期BMJ研究一览

7月第3期BMJ研究一览

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