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CCLM:我国汉族妇女血浆proANP与高尿酸血症的关系如何?

2017-08-06 MedSci MedSci原创

前心房尿钠肽(proANP)与高尿酸血症之间的关系在人群中尚未明确。近日,国际杂志 《Clinical Chemistry and Laboratory Medicine》在线发表一项关于评估中国汉族妇女血浆proANP与高尿酸血症的关系的横断面研究。

前心房尿钠肽(proANP)与高尿酸血症之间的关系在人群中尚未明确。近日,国际杂志 《Clinical Chemistry and Laboratory Medicine》在线发表一项关于评估中国汉族妇女血浆proANP与高尿酸血症的关系的横断面研究。

研究测量了居住在苏州市姑苏区的136030岁以上女性的血浆proANP,血清尿酸和其它传统生物标志物。并在≥45岁的女性和45岁以下的女性中,分析了血浆proANP与高尿酸血症之间的关系。

研究发现,在≥45岁的妇女中,与proANP较低(p = 0.040)的妇女相比,较高proANP(超过中位数)的妇女患高尿酸血优势比(OR[95%置信区间(CI]0.570.34-0.97) 。在校正年龄和其它潜在协变量后,当比较最高和最低等级时,高血浆proANP与≥45岁女性(OR 0.40; 95CI0.19-0.84)的高尿酸血症风险降低相关。相比之下,45岁以下女性的血浆proANP与高尿酸血症无关。研究没有观察到年龄和proANP之间的显著相互作用(p 相互作用 = 0.113)。敏感性分析进一步证实了这些年龄特异性的发现。

研究表明,中国汉族45岁以上老年人血浆proANP与高尿酸血症呈显著负相关趋势,增加血浆proANP应该是中老年妇女高尿酸血症的保护因素。

原始出处:

Zhu, Zhengbao, Zhang, Qiu,Peng, Hao, et al.Association between plasma proANP and hyperuricemia in Chinese Han women: a cross-sectional study.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


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  2. [GetPortalCommentsPageByObjectIdResponse(id=1476756, encodeId=bb2114e6756b3, content=<a href='/topic/show?id=f915102342ea' target=_blank style='color:#2F92EE;'>#高尿酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102342, encryptionId=f915102342ea, topicName=高尿酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05f17331078, createdName=ms622625817193301, createdTime=Tue Aug 08 01:42:00 CST 2017, time=2017-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601905, encodeId=04dc1601905ae, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Aug 08 01:42:00 CST 2017, time=2017-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230707, encodeId=4c29230e0735, content=学了。。。。。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Sun Aug 06 11:36:16 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230704, encodeId=bbac230e0470, content=高尿酸血症与尿纳肽关系研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sun Aug 06 11:23:32 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230695, encodeId=6fcf2306955d, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Sun Aug 06 11:01:56 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
    2017-08-08 sunylz
  3. [GetPortalCommentsPageByObjectIdResponse(id=1476756, encodeId=bb2114e6756b3, content=<a href='/topic/show?id=f915102342ea' target=_blank style='color:#2F92EE;'>#高尿酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102342, encryptionId=f915102342ea, topicName=高尿酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05f17331078, createdName=ms622625817193301, createdTime=Tue Aug 08 01:42:00 CST 2017, time=2017-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1601905, encodeId=04dc1601905ae, content=<a href='/topic/show?id=2f801469e57' target=_blank style='color:#2F92EE;'>#PRO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14697, encryptionId=2f801469e57, topicName=PRO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a60b18898917, createdName=sunylz, createdTime=Tue Aug 08 01:42:00 CST 2017, time=2017-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230707, encodeId=4c29230e0735, content=学了。。。。。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Sun Aug 06 11:36:16 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230704, encodeId=bbac230e0470, content=高尿酸血症与尿纳肽关系研究, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Sun Aug 06 11:23:32 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230695, encodeId=6fcf2306955d, content=不错的,学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NdqKgfW3nMpOkC3jXxiaW2po0PtglY5ZuVjERqKADW4HyMI8bcZXWlKgH7tEP9ULBoBzuQMibia4pr1s9rQPqLvqQJ/0, createdBy=e8c02060444, createdName=中医痴, createdTime=Sun Aug 06 11:01:56 CST 2017, time=2017-08-06, status=1, ipAttribution=)]
    2017-08-06 135****7952平儿

    学了。。。。。。。。。。。。

    0

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    2017-08-06 1e0f8808m18(暂无匿称)

    高尿酸血症与尿纳肽关系研究

    0

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    2017-08-06 中医痴

    不错的,学习了,谢谢分享!

    0

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