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Hypertension:急诊科血压升高是心血管事件的危险因素

2019-12-03 xing.T MedSci原创

由此可见,ED测量的BP提供了重要且未被充分利用的工具,其具有降低与高血压相关的发病率和死亡率的巨大潜力。

在急诊科(ED),经常会观察到高血压(BP),但大部分用于短期内评估患者的健康状况。近日,心血管权威杂志Hypertension上发表了一篇研究文章,研究人员旨在探究ED测量的BP是否与长期的动脉粥样硬化性心血管疾病(ASCVD)、心肌梗死卒中有关,并评估筛查预防ASCVD所需的数量。

在这项队列研究中,参与者来自2010年至2016年间在大学医院就诊的患者,并在急诊科测量了BP。研究人员从瑞典国家患者登记中心获取了所有参与者的结局信息,并采用Cox回归评估了相关性。

在纳入的300193名受试者中,中位随访3.5年,共发生了8999起ASCVD事件。DBP和收缩压均与ASCVD事件、心肌梗死和卒中相关,在SBP处于1级高血压(HR为1.15 [95%CI为1.06-1.24])、2级(HR为1.35,[95%CI为1.25-1.47])和3级(HR为1.63[95%CI为1.49-1.77]),卒中的风险逐渐增加。收缩压≥180mmHg的个体ASCVD的6年累积发生率为12%,而正常水平个体为2%。为了防止在中位随访期间发生一次ASCVD事件,筛查所需的数量估计为151人,而需要治疗的数量估计为71人。ED测量的BP与ASCVD、心肌梗死和卒中有关。ED中记录高BP不容忽视,且是发现和改善高血压的机会。

由此可见,ED测量的BP提供了重要且未被充分利用的工具,其具有降低与高血压相关的发病率和死亡率的巨大潜力。 

原始出处:

Pontus Oras.et al.Elevated Blood Pressure in the Emergency Department A Risk Factor for Incident Cardiovascular Disease.Hypertension.2019.https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.119.14002

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