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生物钟紊乱可能是阿尔茨海默病发病前兆

2018-02-01 周舟 林小春 中国科学报

美国一项新研究发现,在阿尔茨海默病患者表现出丧失记忆症状很多年前,就可能已经出现生物钟紊乱等前兆。这将有助于医生更早发现这种神经退行性疾病。研究成果发表在1月29日出版的《美国医学会杂志·神经病学卷》上。论文第一作者、美国圣路易斯华盛顿大学医学院神经学助理教授埃里克·穆谢克说,研究对象们并非失眠,而是睡眠断断续续,“夜里连续睡8个小时和白天零星地打8个小时盹是非常不同的”。研究团队发表在新一期美国

美国一项新研究发现,在阿尔茨海默病患者表现出丧失记忆症状很多年前,就可能已经出现生物钟紊乱等前兆。这将有助于医生更早发现这种神经退行性疾病。

研究成果发表在1月29日出版的《美国医学会杂志·神经病学卷》上。论文第一作者、美国圣路易斯华盛顿大学医学院神经学助理教授埃里克·穆谢克说,研究对象们并非失眠,而是睡眠断断续续,“夜里连续睡8个小时和白天零星地打8个小时盹是非常不同的”。

研究团队发表在新一期美国《实验医学杂志》上的另一篇论文表明,生理节律混乱也加速了小鼠脑部出现淀粉样蛋白,后者被认为与阿尔茨海默病有关。

此前研究认为,淀粉样蛋白水平会随昼夜起伏,睡眠时其水平会降低,如果睡眠被惊扰或缺乏足够的深度睡眠,淀粉样蛋白水平会上升。

新研究发现,阿尔茨海默病患者还未出现记忆丧失症状时,其生理节律行为表现得更加破碎化,大脑中出现淀粉样蛋白的可能性更大。

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    2018-02-02 巍巍1231

    很好

    0

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