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2017 CPIC指南： HLA 基因型和卡马西平以及奥卡西平的应用（更新版）

2018-02-02 临床药物基因组学实施联盟 Clin Pharmacol Ther. 2018 Feb 2.

HLA基因型卡马西平奥卡西平

2018年2月，临床药物基因组学实施联盟(CPIC)发布了关于 HLA 基因型和卡马西平以及奥卡西平的应用指南2017更新版。 人白细胞抗原（HLA）基因变异芳香类抗惊厥要特定的皮肤不良反应相关，本文的主要目的是解释HLA-B*15:02 和 HLA-A*31:01基因型导致结果指导卡马西平和奥卡西平的使用。

中文标题：

2017 CPIC指南： HLA 基因型和卡马西平以及奥卡西平的应用（更新版）

英文标题：

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.

发布机构：

临床药物基因组学实施联盟

发布日期：

2018-02-02

简要介绍：

2018年2月，临床药物基因组学实施联盟(CPIC)发布了关于 HLA 基因型和卡马西平以及奥卡西平的应用指南2017更新版。

人白细胞抗原（HLA）基因变异芳香类抗惊厥要特定的皮肤不良反应相关，本文的主要目的是解释HLA-B*15:02 和 HLA-A*31:01基因型导致结果指导卡马西平和奥卡西平的使用。

 

拓展指南：与卡马西平相关指南：

相关资料下载：
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2017 CPIC指南： HLA 基因型和卡马西平以及奥卡西平的应用（更新版）
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  1. [GetPortalCommentsPageByObjectIdResponse(id=289740, encodeId=a522289e40ad, content=学习了受益匪浅, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Feb 21 19:52:40 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288774, encodeId=ab6a288e74d8, content=了解了解.继续关注, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sun Feb 18 00:16:42 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288757, encodeId=4615288e57be, content=2018年2月.临床药物基因组学实施联盟(CPIC)发布了关于 HLA 基因型和卡马西平以及奥卡西平的应用指南2017更新版.? 人白细胞抗原(HLA)基因变异芳香类抗惊厥要特定的皮肤不良反应相关.本文的主要目的是解释HLA-B*15:02 和 HLA-A*31:01基因型导致结果指导卡马西平和奥卡西平的使用., beContent=null, objectType=guider, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Feb 17 22:36:48 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288730, encodeId=03e0288e300b, content=学习.谢谢分享., beContent=null, objectType=guider, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Feb 17 21:01:33 CST 2018, time=2018-02-17, status=1, ipAttribution=)]
    2018-02-21 131****1460

    学习了受益匪浅

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=289740, encodeId=a522289e40ad, content=学习了受益匪浅, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Feb 21 19:52:40 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288774, encodeId=ab6a288e74d8, content=了解了解.继续关注, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sun Feb 18 00:16:42 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288757, encodeId=4615288e57be, content=2018年2月.临床药物基因组学实施联盟(CPIC)发布了关于 HLA 基因型和卡马西平以及奥卡西平的应用指南2017更新版.? 人白细胞抗原(HLA)基因变异芳香类抗惊厥要特定的皮肤不良反应相关.本文的主要目的是解释HLA-B*15:02 和 HLA-A*31:01基因型导致结果指导卡马西平和奥卡西平的使用., beContent=null, objectType=guider, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Feb 17 22:36:48 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288730, encodeId=03e0288e300b, content=学习.谢谢分享., beContent=null, objectType=guider, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Feb 17 21:01:33 CST 2018, time=2018-02-17, status=1, ipAttribution=)]
    2018-02-18 1dd8c52fm63(暂无匿称)

    了解了解.继续关注

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=289740, encodeId=a522289e40ad, content=学习了受益匪浅, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Feb 21 19:52:40 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288774, encodeId=ab6a288e74d8, content=了解了解.继续关注, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sun Feb 18 00:16:42 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288757, encodeId=4615288e57be, content=2018年2月.临床药物基因组学实施联盟(CPIC)发布了关于 HLA 基因型和卡马西平以及奥卡西平的应用指南2017更新版.? 人白细胞抗原(HLA)基因变异芳香类抗惊厥要特定的皮肤不良反应相关.本文的主要目的是解释HLA-B*15:02 和 HLA-A*31:01基因型导致结果指导卡马西平和奥卡西平的使用., beContent=null, objectType=guider, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Feb 17 22:36:48 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288730, encodeId=03e0288e300b, content=学习.谢谢分享., beContent=null, objectType=guider, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Feb 17 21:01:33 CST 2018, time=2018-02-17, status=1, ipAttribution=)]
    2018-02-17 有备才能无患

    2018年2月.临床药物基因组学实施联盟(CPIC)发布了关于 HLA 基因型和卡马西平以及奥卡西平的应用指南2017更新版.? 人白细胞抗原(HLA)基因变异芳香类抗惊厥要特定的皮肤不良反应相关.本文的主要目的是解释HLA-B*15:02 和 HLA-A*31:01基因型导致结果指导卡马西平和奥卡西平的使用.

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=289740, encodeId=a522289e40ad, content=学习了受益匪浅, beContent=null, objectType=guider, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Feb 21 19:52:40 CST 2018, time=2018-02-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288774, encodeId=ab6a288e74d8, content=了解了解.继续关注, beContent=null, objectType=guider, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sun Feb 18 00:16:42 CST 2018, time=2018-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288757, encodeId=4615288e57be, content=2018年2月.临床药物基因组学实施联盟(CPIC)发布了关于 HLA 基因型和卡马西平以及奥卡西平的应用指南2017更新版.? 人白细胞抗原(HLA)基因变异芳香类抗惊厥要特定的皮肤不良反应相关.本文的主要目的是解释HLA-B*15:02 和 HLA-A*31:01基因型导致结果指导卡马西平和奥卡西平的使用., beContent=null, objectType=guider, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Sat Feb 17 22:36:48 CST 2018, time=2018-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=288730, encodeId=03e0288e300b, content=学习.谢谢分享., beContent=null, objectType=guider, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Feb 17 21:01:33 CST 2018, time=2018-02-17, status=1, ipAttribution=)]
    2018-02-17 惠映实验室

    学习.谢谢分享.

    0

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