Systems biology is an integrative discipline that seeks to explain the properties and behaviour of complex biological systems in terms of their components and their interactions.

Molecular Systems Biology is a peer-reviewed open access journal that publishes high-quality research in the fields of systems biology, synthetic biology and systems medicine.

The Editors select manuscripts based on their novelty and wide biological significance. Although the primary emphasis of the journal is on molecular components and their interactions, systems studies at the organ level may also be considered. Works describing large-scale datasets will be judged, in part, by the extent to which these datasets are integrated both with each other and with computational models, with the ultimate aim to better understand the dynamic and complex nature of living systems. Reports of new experimental methods will also be considered in the context of this policy.

Topics falling within the scope of the journal include, but are not limited to:

• integrative genome-scale biology 
• quantitative biology
• computational biology 
• metabolic and regulatory networks 
• evolution of genomes and biological networks
• clinical and translational systems biology 
• synthetic biology and genome-scale biological engineering

Molecular Systems Biology publishes research articles as full-length Articles or short Reports. The journal also publishes Methods, Reviews, News & Views, Opinions, Correspondences, Commentaries and Editorials.

Molecular Systems Biology levies an Article Processing Charge (APC) of 4,800 EUROS (5,300 USD/ GBP 4,300) plus tax, where applicable, for Research Articles, Methods or Reports accepted for publication. There are no additional costs (such as page charges or submission charges).

No charges apply for Reviews, News & Views, Commentaries and Correspondences.