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Integrin alpha 6 overexpression promotes lymphangiogenesis and lymphatic metastasis via activating the NF-kappa B signaling pathway in lung adenocarcinoma

期刊: CELLULAR ONCOLOGY, 2022; 45 (1)

Objective It has been reported that tumor-associated lymphangiogenesis plays an important role in lymph node metastasis and contributes to the poor su......

JIF:6.174

The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth

期刊: CELLULAR ONCOLOGY, 2022; 45 (6)

Background CXCL11 has been reported to be up-regulated in hepatocellular carcinoma (HCC) tissues and cancer-associated fibroblasts (CAFs), and CAF-sec......

JIF:6.174

Hippocalcin-like 1 is a key regulator of LDHA activation that promotes the growth of non-small cell lung carcinoma

期刊: CELLULAR ONCOLOGY, 2022; 45 (1)

Background Hippocalcin-like 1 (HPCAL1), a neuronal calcium sensor protein family member, has been reported to regulate cancer growth. As yet, however,......

JIF:6.174

Activation of the HSP27-AKT axis contributes to gefitinib resistance in non-small cell lung cancer cells independent of EGFR mutations

期刊: CELLULAR ONCOLOGY, 2022; 45 (5)

Purpose Although epidermal growth factor receptor (EGFR)-activating mutations in non-small cell lung cancer (NSCLC) usually show sensitivity to first-......

JIF:6.174

Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy

期刊: CELLULAR ONCOLOGY, 2022; 45 (6)

Background Gastric cancer imposes a substantial global health burden despite its overall incidence decrease. A broad spectrum of inherited, environmen......

JIF:6.174

Molecular signaling in pancreatic ductal metaplasia: emerging biomarkers for detection and intervention of early pancreatic cancer

期刊: CELLULAR ONCOLOGY, 2022; 45 (2)

Pancreatic ductal metaplasia (PDM) is the transformation of potentially various types of cells in the pancreas into ductal or ductal-like cells, which......

JIF:6.174

Proteomic characterisation of prostate cancer intercellular communication reveals cell type-selective signalling and TMSB4X-dependent fibroblast reprogramming

期刊: CELLULAR ONCOLOGY, 2022; 45 (6)

Background In prostate cancer, the tumour microenvironment (TME) represents an important regulator of disease progression and response to treatment. I......

JIF:6.174

Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy

期刊: CELLULAR ONCOLOGY, 2022; 45 (6)

Purpose Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) form a rare and remarkably heterogeneous group of tumors. Therefore, establishing pe......

JIF:6.174

Distinct expression and function of breast cancer metastasis suppressor 1 in mutant P53 glioblastoma

期刊: CELLULAR ONCOLOGY, 2022; 45 (6)

Purpose Glioblastoma (GBM) is the most malignant subtype of astrocytic tumors with the worst prognosis in all its progressive forms. Breast cancer met......

JIF:6.174

PKP1 and MYC create a feedforward loop linking transcription and translation in squamous cell lung cancer

期刊: CELLULAR ONCOLOGY, 2022; 45 (2)

Purpose Plakophilin 1 (PKP1) is well-known as an important component of the desmosome, a cell structure specialized in spot-like cell-to-cell adhesion......

JIF:6.174

Heterogeneity, inherent and acquired drug resistance in patient-derived organoid models of primary liver cancer

期刊: CELLULAR ONCOLOGY, 2022; 45 (5)

Purpose We aimed to elucidate the applicability of tumor organoids for inherent drug resistance of primary liver cancer (PLC) and mechanisms of acquir......

JIF:6.174

HDAC6: A unique HDAC family member as a cancer target

期刊: CELLULAR ONCOLOGY, 2022; 45 (5)

Background HDAC6, a structurally and functionally distinct member of the HDAC family, is an integral part of multiple cellular functions such as cell ......

JIF:6.174

Spheroid-induced heterogeneity and plasticity of uveal melanoma cells

期刊: CELLULAR ONCOLOGY, 2022; 45 (2)

Purpose The mechanism underlying cancer heterogeneity and plasticity remains elusive, in spite of the fact that multiple hypotheses have been put forw......

JIF:6.174

SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans

期刊: CELLULAR ONCOLOGY, 2022; 45 (3)

Background Solute carrier family 26 member (SLC26A9) is a Cl- uniporter with very high expression levels in the gastric mucosa. Here, we describe morp......

JIF:6.174

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