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Metabolomics screening of serum biomarkers for occupational exposure of titanium dioxide nanoparticles

期刊: NANOTOXICOLOGY, 2021; 15 (6)

Although nanotoxicology studies have shown that respiratory exposure of titanium dioxide nanoparticles (TiO2 NPs) could induce adverse health effects,......

Stabilization of Nrf2 leading to HO-1 activation protects against zinc oxide nanoparticles-induced endothelial cell death

期刊: NANOTOXICOLOGY, 2021; 15 (6)

With the abundant production and wide application of zinc oxide nanoparticles (ZnONPs), the potential health risks of ZnONPs have raised serious conce......

Polystyrene nanoplastics exposure caused defective neural tube morphogenesis through caveolae-mediated endocytosis and faulty apoptosis

期刊: NANOTOXICOLOGY, 2021; 15 (7)

Growing evidence demonstrated that bioaccumulation of polystyrene nanoplastics (PS-NPs) in various organisms including human beings caused destructive......

MiR-939-5p suppresses PM2.5-induced endothelial injury via targeting HIF-1 alpha in HAECs

期刊: NANOTOXICOLOGY, 2021; 15 (5)

Ambient air pollution is a leading cause of non-communicable disease in the world. PM2.5 has the potential to change the miRNAs profiles, which in tur......

Carbon nanotubes promote alveolar macrophages toward M2 polarization mediated epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation

期刊: NANOTOXICOLOGY, 2021; 15 (5)

With substantial progress of nanotechnology, carbon nanotubes (CNTs) are widely used in a variety of industrial and commercial applications. There is ......

Iron oxide nanoparticles aggravate hepatic steatosis and liver injury in nonalcoholic fatty liver disease through BMP-SMAD-mediated hepatic iron overload

期刊: NANOTOXICOLOGY, 2021; 15 (6)

Nonalcoholic fatty liver disease (NAFLD) is the leading hepatic manifestation of metabolic syndrome worldwide, and is clinically accompanied by iron o......

Time-course effect of ultrasmall superparamagnetic iron oxide nanoparticles on intracellular iron metabolism and ferroptosis activation

期刊: NANOTOXICOLOGY, 2021; 15 (3)

Ferroptosis is an iron-dependent cell death caused by excessive peroxidation of polyunsaturated fatty acids. It can be activated by iron-based nanopar......

Mechanisms of nanotoxicity - biomolecule coronas protect pathological fungi against nanoparticle-based eradication

期刊: NANOTOXICOLOGY, 2020; 14 (9)

Whereas nanotoxicity is intensely studied in mammalian systems, our knowledge of desired or unwanted nano-based effects for microbes is still limited.......

miR-205/IRAK2 signaling pathway is associated with urban airborne PM2.5-induced myocardial toxicity

期刊: NANOTOXICOLOGY, 2020; 14 (9)

Exposure to fine particulate matter (PM2.5) is closely linked with cardiovascular diseases. However, the underlying mechanism of PM2.5 on cardiac func......

The nanomaterial-induced bystander effects reprogrammed macrophage immune function and metabolic profile

期刊: NANOTOXICOLOGY, 2020; 14 (8)

Bystander effects in biological systems are the responses shown by nontargeted neighboring cells, and critical to the bio-nano interface interactions.......

Effects of titanium dioxide nanoparticles on nutrient absorption and metabolism in rats: distinguishing the susceptibility of amino acids, metal elements, and glucose

期刊: NANOTOXICOLOGY, 2020; 14 (10)

Food grade titanium dioxide (TiO2) containing nanofractions, is commonly applied to whiten and brighten food products, which put consumers under healt......

Zinc ferrate nanoparticles for applications in medicine: synthesis, physicochemical properties, regulation of macrophage functions, andin vivosafety evaluation

期刊: NANOTOXICOLOGY, 2020; 14 (10)

Zinc ferrate nanoparticles (ZnFe(2)O(4)NPs) have attracted enormous interest as potential nanomaterials. The purpose of this study was to examine thei......

In vitro and in vivo immunotoxicity of PEGylated Cd-free CuInS2/ZnS quantum dots

期刊: NANOTOXICOLOGY, 2020; 14 (3)

The annual increase in the production and the use of engineering quantum dots (QDs) have led to concern about exposure and safety of QDs. To resolve t......

Repeated administrations of Mn3O4 nanoparticles cause testis damage and fertility decrease through PPAR-signaling pathway

期刊: NANOTOXICOLOGY, 2020; 14 (3)

Potential health hazards of nanomaterials on male reproductive system have received raising concerns. Even though Mn3O4 nanoparticles (Mn3O4-NPs) is h......

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