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Time-course effect of ultrasmall superparamagnetic iron oxide nanoparticles on intracellular iron metabolism and ferroptosis activation

Gao, JL; Zhou, HG; Zhao, YJ; Lu, L; Zhang, JZ; Cheng, WT; Song, XX; Zheng, YX; Chen, CY; Tang, JL

Tang, JL (corresponding author), Qingdao Univ, Sch Publ Hlth, 38,Dengzhou Rd, Qingdao 266071, Peoples R China.; Chen, CY (corresponding author), Natl Ctr Nanosci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, 2,1st Northern St, Beijing 100080, Peoples R China.; Chen, CY (corresponding author), Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, 2,1st Northern St, Beijing 100080, Peoples R China.

NANOTOXICOLOGY, 2021; 15 (3): 366

Abstract

Ferroptosis is an iron-dependent cell death caused by excessive peroxidation of polyunsaturated fatty acids. It can be activated by iron-based nanopar......

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