期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (3)
Compound repurposing is an important strategy for the identification of effective treatment options against SARS-CoV-2 infection and COVID-19 disease.......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (1)
The instrumental role of CK2 in the SARS-CoV-2 infection has pointed out this protein kinase as promising therapeutic target in COVID-19. Anti-SARS-Co......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (2)
The development of therapeutic biosimilar antibodies has become an important driving force of the modern biopharmaceutical industry. In this study, ph......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (2)
A series of bone-targeting EP4 receptor agonist conjugate prodrugs were prepared wherein a potent EP4 receptor agonist was bound to a biologically ina......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (1)
Di(2-ethylhexyl) phthalate (DEHP) is a synthetic chemical and widely used as a plasticizer. Humans can be exposed to DEHP through direct contact or en......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (3)
Kidney fibrosis is accompanied by vascular dysfunction. Discovering new ways to ameliorate dysfunctional angiogenesis may bypass kidney fibrosis. YAP ......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (2)
The clinical applications of many photosensitizers (PSs) are limited because of their poor water solubility, weak tissue penetration, low chemical pur......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (2)
Drug induced cholestasis (DIC) is complexly associated with dysbiosis of the host-gut microbial cometabolism of bile acids (BAs). Murine animals are n......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (4)
SARS-CoV-2 main protease (M-Pro) is a cysteine protease that mediates the cleavage of viral polyproteins and is a validated antiviral drug target. M-P......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (3)
Niemann-Pick disease type C1 (NPC1) is a rare genetic cholesterol storage disorder caused by mutations in the NPC1 gene. Mutations in this transmembra......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2021; 4 (1)
Simultaneous determination of the content of six alkaloids (aconitine, hypoaconitine, mesaconitine, benzoylaconine, benzoylhypaconine, and benzoylmesa......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2022; 5 (7)
Andrographolide (andro) and its derivatives have been reported to have antitumor activity by arresting the cell cycle. However, the more precise mecha......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2022; 5 (9)
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal lung disease. Rho-associated protein kinases (ROCK) 1/2 are promising therape......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2022; 5 (12)
The role of the NFL-TBS.40-63 peptide is to destroy the microtubule network of target glioma cancer cells. Recently, we have conceived a gold-complex ......
期刊： ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2022; 5 (9)
Trefoil factor 3 (TFF3) is a secreted protein with an established oncogenic function and a highly significant association with clinical progression of......
