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Targeting PRAS40: a novel therapeutic strategy for human diseases

Zhou, Q; Tang, SS; Zhang, XH; Chen, LX

Zhang, XH (corresponding author), Dongkou Peoples Hosp, Orthoped Dept, Dongkou 422300, Hunan, Peoples R China.; Chen, LX (corresponding author), Univ South China, Hunan Prov Key Lab Tumor Microenvironm Respons Dr, Hunan Prov Cooperat Innovat Ctr Mol Target, New Drug Study,Inst Pharm & Pharmacol, 28 Changsheng Rd, Hengyang 421001, Hunan, Peoples R China.

JOURNAL OF DRUG TARGETING, 2021; 29 (7): 703

Abstract

Proline-rich Akt substrate of 40 kD (PRAS40) is not only the substrate of protein kinase B (PKB/Akt), but also the binding protein of 14-3-3 protein. ......

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