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Pharmacokinetics of Eltrombopag in Healthy Chinese Subjects and Effect of Sex and Genetic Polymorphism on its Pharmacokinetic and Pharmacodynamic Variability

Chen, JL; Xu, YC; Lou, HG; Jiang, B; Shao, R; Yang, DD; Hu, Y; Ruan, ZR

Ruan, ZR (corresponding author), Zhejiang Univ, Sch Med, Ctr Clin Pharmacol, Affiliated Hosp 2, 88 Jiefang Rd, Hangzhou 310009, Zhejiang, Peoples R China.

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, ; ():

Abstract

Background and Objective Eltrombopag is the first oral, small-molecule, non-peptide thrombopoietin receptor agonist for the treatment of idiopathic th......

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