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ROR2 blockade as a therapy for osteoarthritis

Thorup, AS; Strachan, D; Caxaria, S; Poulet, B; Thomas, BL; Eldridge, SE; Nalesso, G; Whiteford, JR; Pitzalis, C; Aigner, T; Corder, R; Bertrand, J; Dell'Accio, F

Thorup, AS; Dell'Accio, F (corresponding author), Queen Mary Univ London, Barts & London Sch Med & Dent, William Harvey Res Inst, London EC1M 6BQ, England.

SCIENCE TRANSLATIONAL MEDICINE, 2020; 12 (561):

Abstract

Osteoarthritis is characterized by the loss of the articular cartilage, bone remodeling, pain, and disability. No pharmacological intervention can cur......

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