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Off-target effects of RNAi correlate with the mismatch rate between dsRNA and non-target mRNA

Chen, JS; Peng, YC; Zhang, HN; Wang, KX; Zhao, CQ; Zhu, GH; Palli, SR; Han, ZJ

Han, ZJ (corresponding author), Nanjing Agr Univ, Plant Protect Dept, Weigang 1, Nanjing, Peoples R China.

RNA BIOLOGY, ; ():

Abstract

RNAi is a potent technique for the knockdown of target genes. However, its potential off-target effects limit the widespread applications in both reve......

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