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TREM1 activation of myeloid cells promotes antitumor immunity

Juric, V; Mayes, E; Binnewies, M; Lee, T; Canaday, P; Pollack, JL; Rudolph, J; Du, XY; Liu, VM; Dash, S; Palmer, R; Jahchan, NS; Ramoth, AJ; Lacayo, S; Mankikar, S; Norng, M; Brassell, C; Pal, A; Chan, C; Lu, E; Sriram, V; Streuli, M; Krummel, MF; Baker, KP; Liang, LD

Baker, KP; Liang, LD (通讯作者),Pionyr Immunotherapeut, 2 Tower Pl,Suite 800, South San Francisco, CA 94080 USA.

SCIENCE TRANSLATIONAL MEDICINE, 2023; 15 (711):

Abstract

Myeloid cells in the tumor microenvironment (TME) can exist in immunosuppressive and immunostimulatory states that impede or promote antitumor immunit......

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