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盘点:叶酸:你所知道的与不知道的

2016-05-24 MedSci 梅斯医学

最近,叶酸越来越多的出现在了人们的视野之中,尤其是对于孕妇,常常被建议补充叶酸。那么,叶酸的补充对人尤其是孕妇有何益处?补充叶酸实际上会产生哪些效果?盲目补充叶酸有何危害?小编将为大家一一盘点。

最近,叶酸越来越多的出现在了人们的视野之中,尤其是对于孕妇,常常被建议补充叶酸。那么,叶酸的补充对人尤其是孕妇有何益处?补充叶酸实际上会产生哪些效果?盲目补充叶酸有何危害?小编将为大家一一盘点。

补充叶酸好处多:


CSPPT 研究以及发表在JAMA上的研究结果显示,在中国两万多无心肌梗死及卒中病史的成年高血压患者中,以依那普利叶酸片为基础降压治疗,降低了高达21%的首次脑卒中风险,即使是单纯补充叶酸,也有利于减少脑卒中乃至心脑血管疾病的发生率。
 

澳大利亚科学家在一项大规模人群的研究发现,缺乏叶酸会引起听力损失。其结果显示,如果每公升叶酸含量低于11纳摩尔时,人有34%的可能性患听力损失风险。
 

经研究发现,在怀孕前每天摄入至少0.4毫克的叶酸,可进一步降低神经管缺陷(简称NTDs,包括脊柱裂和相关疾病)的发生率。
 

美国明尼苏达大学博士后研究员Kimberly J. Johnson博士带领完成了一项研究,该研究表明含叶酸食品可降低肾母细胞瘤和儿童原始神经外胚层瘤(PNETs)的患病率。

盲目补充叶酸也是有害的:


来自西班牙的Desirée Valera-Gran医生对一岁儿童的神经心理发育展开调查。多变量分析后发现,相比于每天叶酸补充量在400-1000ug的孕妇,怀孕期间每天叶酸补充量超过5000ug的孕妇其子女的精神运动量表分数发育显著低下,精神运动发育迟缓的风险也会升高。
 

在美国时间5月14日结束的国际自闭症科研大会(IMFAR)上,来自约翰霍普金斯医学院公共健康学院的科研小组报道,新生儿母亲血液中同时存在高含量的叶酸和维生素B12(VB12)时,新生儿患自闭症的风险提高了17倍。
 

塔夫茨大学美国农业部人类营养研究中心(HNRCA)的研究人员进行了一项研究,发现过量摄入叶酸将会导致年龄较大的个体NK细胞活性降低,从而降低其免疫力。

破除关于叶酸的这些谣言:

从2007年12月至2012年8月进行的一项研究表明,产前补充铁叶酸合剂与否,对于婴儿6个月内的全因死亡率没有显著性差异。
 

曾经有学者认为每日5mg的叶酸补充会提高乳腺癌及其他癌变的风险,Taylor CM等人对此进行长达10年随访延伸研究,结果表明孕妇其将来的生活中乳腺癌或其他癌症死亡率不会因为孕期每天摄入5mg叶酸而增加。
 
小编认为,叶酸应该补充,尤其是对于孕妇。但补充多少应慎重决定,最好能咨询相关医生或专业人员。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=87087, encodeId=0e348e08741, content=什么都不可过量补充, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=301d1720835, createdName=1dec631em90(暂无匿称), createdTime=Wed May 25 12:04:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87031, encodeId=e5b68e03113, content=这能准吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87032, encodeId=68088e032d9, content=数据可信?, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86958, encodeId=74258695850, content=被楼上打败了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue May 24 18:51:00 CST 2016, time=2016-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86929, encodeId=54688692931, content=酸应该补充,尤其是对于孕妇。但补充多少应慎重决定,最好能咨询相关医生或专业人员。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Tue May 24 14:04:00 CST 2016, time=2016-05-24, status=1, ipAttribution=)]
    2016-05-25 1dec631em90(暂无匿称)

    什么都不可过量补充

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=87087, encodeId=0e348e08741, content=什么都不可过量补充, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=301d1720835, createdName=1dec631em90(暂无匿称), createdTime=Wed May 25 12:04:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87031, encodeId=e5b68e03113, content=这能准吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87032, encodeId=68088e032d9, content=数据可信?, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86958, encodeId=74258695850, content=被楼上打败了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue May 24 18:51:00 CST 2016, time=2016-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86929, encodeId=54688692931, content=酸应该补充,尤其是对于孕妇。但补充多少应慎重决定,最好能咨询相关医生或专业人员。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Tue May 24 14:04:00 CST 2016, time=2016-05-24, status=1, ipAttribution=)]
    2016-05-25 milkshark

    这能准吗

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=87087, encodeId=0e348e08741, content=什么都不可过量补充, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=301d1720835, createdName=1dec631em90(暂无匿称), createdTime=Wed May 25 12:04:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87031, encodeId=e5b68e03113, content=这能准吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87032, encodeId=68088e032d9, content=数据可信?, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86958, encodeId=74258695850, content=被楼上打败了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue May 24 18:51:00 CST 2016, time=2016-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86929, encodeId=54688692931, content=酸应该补充,尤其是对于孕妇。但补充多少应慎重决定,最好能咨询相关医生或专业人员。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Tue May 24 14:04:00 CST 2016, time=2016-05-24, status=1, ipAttribution=)]
    2016-05-25 milkshark

    数据可信?

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=87087, encodeId=0e348e08741, content=什么都不可过量补充, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=301d1720835, createdName=1dec631em90(暂无匿称), createdTime=Wed May 25 12:04:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87031, encodeId=e5b68e03113, content=这能准吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87032, encodeId=68088e032d9, content=数据可信?, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86958, encodeId=74258695850, content=被楼上打败了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue May 24 18:51:00 CST 2016, time=2016-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86929, encodeId=54688692931, content=酸应该补充,尤其是对于孕妇。但补充多少应慎重决定,最好能咨询相关医生或专业人员。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Tue May 24 14:04:00 CST 2016, time=2016-05-24, status=1, ipAttribution=)]
    2016-05-24 ssummer

    被楼上打败了!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=87087, encodeId=0e348e08741, content=什么都不可过量补充, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=301d1720835, createdName=1dec631em90(暂无匿称), createdTime=Wed May 25 12:04:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87031, encodeId=e5b68e03113, content=这能准吗, beContent=null, objectType=article, channel=null, level=null, likeNumber=138, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=87032, encodeId=68088e032d9, content=数据可信?, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Wed May 25 07:44:00 CST 2016, time=2016-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86958, encodeId=74258695850, content=被楼上打败了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue May 24 18:51:00 CST 2016, time=2016-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=86929, encodeId=54688692931, content=酸应该补充,尤其是对于孕妇。但补充多少应慎重决定,最好能咨询相关医生或专业人员。, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Tue May 24 14:04:00 CST 2016, time=2016-05-24, status=1, ipAttribution=)]
    2016-05-24 lovetcm

    酸应该补充,尤其是对于孕妇。但补充多少应慎重决定,最好能咨询相关医生或专业人员。

    0

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