J Am Heart Assoc：贫血可增加卒中后的死亡率

2016-08-21 MedSci MedSci原创

据发表于Journal of the American Heart Association 的一项新的研究表明，贫血增加了老年患者中风的死亡率。小M对此进行了整理，具体研究如下：背景与目的目前对于血红蛋白的水平和贫血对脑卒中死亡率的影响仍存在争议。本研究旨在系统性评估二者之间的关联并量化研究证据。方法和结果使用英国区域性卒中登记册，研究人员共分析了8013名卒中患者

据发表于Journal of the American Heart Association 的一项新的研究表明，贫血增加了老年患者中风的死亡率。小M对此进行了整理，具体研究如下：

背景与目的

目前对于血红蛋白的水平和贫血对脑卒中死亡率的影响仍存在争议。本研究旨在系统性评估二者之间的关联并量化研究证据。

方法和结果

使用英国区域性卒中登记册，研究人员共分析了8013名卒中患者（平均年龄为77.81岁）连续收治11年以上（2003年1月至2015年5月）的数据。使用多元回归模型控制混杂因素后，在不同时间点(7和14 天; 1, 3,和6 个月; 1年)使用性别特定值评估血红蛋白水平和贫血对死亡率的影响。

该研究队列中24.5%的研究对象存在贫血，且在卒中后1年时最可能增加死亡的发生风险。男性出血性卒中的患者中，该关联并不一致。血红蛋白升高也与死亡率的增加有关，这主要是在第一个月内。

然后研究人员使用EMBASE和MEDLINE数据库进行了一项系统回顾，共20项研究符合纳入标准。与从目前的研究队列相结合时，纳入的研究对象共有29943名脑卒中患者。进行荟萃分析以定量证据的质量。结果发现，贫血与缺血性脑卒中（8项研究；比值比1.97 [ 95%可信区间1.57-2.47）和出血性脑卒中（4项研究；比值比1.46 [ 95%可信区间1.23-1.74））的死亡率增加有关。

结论

强有力的证据表明，贫血增加了患者脑卒中的死亡率。在此人群中采取有针对性的干预措施，或可改善结果，并需要进一步的评估。

原始出处：

Raphae S. Barlas, Katie Honney, et al., Impact of Hemoglobin Levels and Anemia on Mortality in Acute Stroke: Analysis of UK Regional Registry Data, Systematic Review, and Meta‐Analysis. J Am Heart Assoc2016. doi:10.1161/JAHA.115.003019.

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2016-10-08 ylzr123

关注值得学习。赞！好文有待探究。

121 0
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2016-09-03 李东泽

很好，不错，以后会多学习

122 0
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2017-01-30 waiwai3039

#卒中后#

83 0
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createdName=李东泽, createdTime=Sat Sep 03 00:03:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671260, encodeId=6ac016e12602e, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 30 23:38:00 CST 2017, time=2017-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356102, encodeId=c250135610268, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Aug 23 04:38:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562380, encodeId=6bb3156238052, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Aug 23 04:38:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102440, encodeId=592f102440c5, content=谢谢了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Tue Aug 23 00:48:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102274, encodeId=eaf41022e47d, content=进一步学习各科知识，才能更好的服务病人，减轻病人的痛苦, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Mon Aug 22 15:22:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102252, encodeId=54d310225255, content=学习起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Mon Aug 22 11:45:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102202, encodeId=6894102202f3, content=可以保存下来！, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Aug 22 10:10:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102201, encodeId=34ad10220193, content=身在基层，努力学习，才能提高学术于修养！进一步了解各科知识，才能更好的为人民服务，减轻病人们的疾患！, beContent=null, 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2016-08-23 zhaojie88

#ART#

95 0
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createdName=李东泽, createdTime=Sat Sep 03 00:03:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671260, encodeId=6ac016e12602e, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 30 23:38:00 CST 2017, time=2017-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356102, encodeId=c250135610268, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Aug 23 04:38:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562380, encodeId=6bb3156238052, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Aug 23 04:38:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102440, encodeId=592f102440c5, content=谢谢了，谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=122, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Tue Aug 23 00:48:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102274, encodeId=eaf41022e47d, content=进一步学习各科知识，才能更好的服务病人，减轻病人的痛苦, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Mon Aug 22 15:22:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102252, encodeId=54d310225255, content=学习起来, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Mon Aug 22 11:45:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102202, encodeId=6894102202f3, content=可以保存下来！, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Aug 22 10:10:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102201, encodeId=34ad10220193, content=身在基层，努力学习，才能提高学术于修养！进一步了解各科知识，才能更好的为人民服务，减轻病人们的疾患！, beContent=null, 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2016-08-23 slcumt

#HEART#

65 0
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createdName=李东泽, createdTime=Sat Sep 03 00:03:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1671260, encodeId=6ac016e12602e, content=<a href='/topic/show?id=9f4e360191a' target=_blank style='color:#2F92EE;'>#卒中后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36019, encryptionId=9f4e360191a, topicName=卒中后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ff7426824786, createdName=waiwai3039, createdTime=Mon Jan 30 23:38:00 CST 2017, time=2017-01-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356102, encodeId=c250135610268, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, 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likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151005/IMG5612955936CFA7964.jpg, createdBy=18621654109, createdName=Guoxj3234, createdTime=Mon Aug 22 11:45:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102202, encodeId=6894102202f3, content=可以保存下来！, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160817/IMG57B3C3F6DC2FD8753.jpg, createdBy=81321934679, createdName=1e0d99ddm02(暂无匿称), createdTime=Mon Aug 22 10:10:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102201, encodeId=34ad10220193, content=身在基层，努力学习，才能提高学术于修养！进一步了解各科知识，才能更好的为人民服务，减轻病人们的疾患！, beContent=null, 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2016-08-23 1e0ece0dm09(暂无匿称)

谢谢了，谢谢分享

122 0
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2016-08-22 知难而进

进一步学习各科知识，才能更好的服务病人，减轻病人的痛苦

121 0
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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K46ZAxBHmHsph32KkfsWGwmickB6RsCUD8KruE4vo5CpvXfdu16GBpp4ibh6WJu1o9iatP1LWKDmvmic/0, createdBy=be6f1940165, createdName=1e0ece0dm09(暂无匿称), createdTime=Tue Aug 23 00:48:00 CST 2016, time=2016-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102274, encodeId=eaf41022e47d, content=进一步学习各科知识，才能更好的服务病人，减轻病人的痛苦, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Mon Aug 22 15:22:00 CST 2016, time=2016-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=102252, encodeId=54d310225255, content=学习起来, beContent=null, objectType=article, channel=null, level=null, 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2016-08-22 Guoxj3234

学习起来

115 0
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2016-08-22 1e0d99ddm02(暂无匿称)

可以保存下来！

65 0
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2016-08-22 1e0d99ddm02(暂无匿称)

身在基层，努力学习，才能提高学术于修养！进一步了解各科知识，才能更好的为人民服务，减轻病人们的疾患！

68 0