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Graefes Arch Clin Exp Ophthalmol:德国青光眼的患病率调查研究

2018-05-26 cuiguizhong MedSci原创

德国美因茨大学医学中心眼科的H?hnR近日在Graefes Arch Clin Exp Ophthalmol发表了一篇文章,他们根据国际地理和流行病学眼科学会(ISGEO)分类标准在德国成年人中确定青光眼的患病概率。

德国美因茨大学医学中心眼科的H?hnR近日在Graefes Arch Clin Exp Ophthalmol发表了一篇文章,他们根据国际地理和流行病学眼科学会(ISGEO)分类标准在德国成年人中确定青光眼的患病概率。

Gutenberg健康研究是一项在德国中西部莱茵美因地区进行的人群前瞻性队列研究,共有15010名参与者参与其中。在这项研究中,第一批5000名受试者的年龄介于35至74岁之间。通过非散瞳眼底照相机(Visucam TM)获得视盘图片并使用Visupac TM软件进行分析。青光眼患病概率通过下面两步确定。首先,根据ISGEO分类,"超常规对象"(正常视野)作为研究参考。第二步,他们还通过分位数回归的方法,兼顾视盘面积(DA)与垂直杯盘比率之间的关系。

结果他们发现,分析的样本中确诊青光眼的患病概率为1.44%(n = 72)。调整视盘面积后的患病概率为1.34%(n = 67)。随着年龄的增长,两种模型的患病率逐渐增加(分别从0.9%到2.4%)。在两种模型中,小面积(<1.6 mm2)视盘中没有发现青光眼病例。中度视盘中的青光眼患病率为1.0%(无DA调整)与1.6%(DA调整),大面积视盘中的青光眼患病率为5.6%与2.5%。

因此,他们认为,德国青光眼的患病率与其他欧洲人群类似,在年长受试者中患病率稍高。他们的分析还强调,通过流行病学分析发现,在青光眼诊断时,视杯视盘比可以用于辅助诊断

原文出处:

Hohn, R., et al., Prevalence of glaucoma in Germany: results from the Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol, 2018.

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    2018-05-31 清风拂面

    谢谢分享学习

    0

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    2018-05-30 yfjms

    学习

    0

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    2018-05-28 zhaojie88
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    2018-05-27 三生有幸9135

    学习学习学习

    0

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    2018-05-27 飛歌

    学习了很有用

    0

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    2018-05-26 changjiu

    学习一下谢谢

    0

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    2018-05-26 中医痴

    不错的.学习了.谢谢分享!

    0

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