期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (7)
The double-stranded RNA sensor kinase PKR is one of four integrated stress response (ISR) sensor kinases that phosphorylate the a subunit of eukaryoti......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (9)
Upon antigen binding, the B cell receptor (BCR) undergoes clustering to form a signalosome that propagates downstream signaling required for normal B ......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 222 (1)
Liquid-liquid phase separation (LLPS) has emerged as a fundamental mechanism to compartmentalize biomolecules into membraneless organelles. In this is......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (2)
In this review, Braschi et al. provide an updated consensus nomenclature for components of dynein motors and their assembly factors. Dyneins are highl......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (5)
Establishment of apicobasal polarity and the organization of the cytoskeleton must operate coordinately to ensure proper epithelial cell shape and fun......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (5)
SNX-RGS proteins are molecular tethers localized to multiple interorganelle contact sites that exhibit roles in cellular metabolism. Here, we highligh......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (7)
Sheldon Penman made major contributions to the field of RNA synthesis and, more broadly, the nexus between cellular form and gene readout. He will be ......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (8)
Membrane contact sites are specialized platforms formed between most organelles that enable them to exchange metabolites and influence the dynamics of......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (10)
Liquid-liquid phase separation (LLPS) triages protein cargoes for autophagic degradation. In this issue, Ohshima et al. (2022. J. Cell Biol.) demonstr......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (12)
Zhu et al. review the current knowledge on how mTORC1 activity is connected to cell death regulation through metabolic and signaling pathways. The mec......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (2)
The physiological mechanisms driving synapse formation are elusive. Although numerous signals are known to regulate synapses, it remains unclear which......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (4)
Wang et al. identify Peln1 as a key chromatin lncRNA that controls the pluripotency exit in stem cells by trans regulating the Oct4 promoter and intra......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (4)
Epithelial cell-cell junctions remodel in response to mechanical stimuli to maintain barrier function. Previously, we found that local leaks in tight ......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (4)
Cell migration is a complex process that involves coordinated changes in membrane transport and actin cytoskeleton dynamics. Ras-like small monomeric ......
期刊： JOURNAL OF CELL BIOLOGY, 2022; 221 (5)
The apical junction of epithelial cells can generate force to control cell geometry and perform contractile processes while maintaining barrier functi......
