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Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data

van der Lee, M; Allard, WG; Vossen, RHAM; Baak-Pablo, RF; Menafra, R; Deiman, BALM; Deenen, MJ; Neven, P; Johansson, I; Gastaldello, S; Ingelman-Sundberg, M; Guchelaar, HJ; Swen, JJ; Anvar, SY

Swen, JJ; Anvar, SY (corresponding author), Leiden Univ Med Ctr, Dept Clin Pharm & Toxicol, NL-2333 ZA Leiden, Netherlands.; Swen, JJ; Anvar, SY (corresponding author), Leiden Network Personalised Therapeut, NL-2333 ZA Leiden, Netherlands.; Anvar, SY (corresponding author), Leiden Univ Med Ctr, Dept Human Genet, NL-2333 ZA Leiden, Netherlands.; Anvar, SY (corresponding author), Leiden Univ Med Ctr, Leiden Genome Technol Ctr, NL-2333 ZA Leiden, Netherlands.

SCIENCE TRANSLATIONAL MEDICINE, 2021; 13 (603):

Abstract

Pharmacogenomics is a key component of personalized medicine that promises safer and more effective drug treatment by individualizing drug choice and ......

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