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J Oral Rehabil:改善帕金森病患者的口腔功能和卫生状况

2020-08-03 MedSci原创 MedSci原创

帕金森病(PD)是一种进行性神经退行性疾病。它与减少口腔健康和口腔功能受损有关,但除了推荐进行牙科就诊和流口水治疗外,很少有文献记载的牙病治疗方案。本研究旨在评估标准化家庭锻炼下颌张开和咀嚼程序以及受

帕金森病(PD)是一种进行性神经退行性疾病。它与减少口腔健康和口腔功能受损有关,但除了推荐进行牙科就诊和流口水治疗外,很少有文献记载的牙病治疗方案。本研究旨在评估标准化家庭锻炼下颌张开和咀嚼程序以及受过培训的牙医指导和控制的家庭口腔卫生措施的效果。

29名中度至晚期PD患者(中位数65岁)在知情同意后参与了该项目。他们在神经内科进行了随访,能够配合,并进行了稳定的治疗,有9人还进行了深部脑刺激。干预措施为个体口腔卫生指导、下颌张开训练(JawTrainer)、唇部和咀嚼练习(Ulmer口腔筛查和Proxident氟化胶)。该研究以随机对照研究的方式进行。在2个月和4个月后评估治疗效果。主要结果是最大的无辅助下颌张开能力、标准苹果片的咀嚼时间和简化碎片指数。使用Wilcoxon匹配对检验和Mann-Whitney U检验对结果进行分析(显著性水平P < .05)。

结果显示,干预开始2个月后,下颌张口度、咀嚼时间和卫生状况均有明显改善,分别为6%、49%和25%,4个月后改善仍显著。2个月对照期后未发现明显变化,未进行干预。

总之,简单的措施在临床上有实质性的显著效果,尽管PD具有渐进性,但还是有希望的。

原始出处:

Sara BaramMerete KarlsborgMerete Bakke. Improvement of oral function and hygiene in Parkinson's disease: A randomised controlled clinical trial. J Oral Rehabil. 2020 Mar;47(3):370-376.  doi: 10.1111/joor.12924.

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    2021-05-24 小几洁
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    2020-08-05 qjddjq
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